检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:陈倩[1] 唐子淇 丁银元 CHEN Qian;TANG Ziqi;DING Yinyuan(Centre for Lipid Research&Chongqing Key Laboratory of Metabolism on Lipid and Glucose,Chongqing Medical University,Chongqing 400016)
机构地区:[1]重庆医科大学脂质研究中心脂糖代谢性疾病重庆市重点实验室,重庆市400016
出 处:《中国动脉硬化杂志》2025年第3期194-201,共8页Chinese Journal of Arteriosclerosis
基 金:国家自然科学基金项目(82270854);重庆市自然科学基金项目(cstc2020jcyj-msxmX0408)。
摘 要:肠道菌群参与调节宿主免疫、消化、肠道内分泌系统功能,且通过代谢产物影响宿主神经信号传导及营养物质代谢。血管钙化是指磷酸钙在血管壁沉积,可继发于慢性肾病、动脉粥样硬化、糖尿病及骨质疏松症等代谢性疾病。近二十年研究结果表明,肠道菌群的组成和功能改变及其代谢产物与上述代谢性疾病血管钙化的发生存在密切联系。文章针对肠道菌群的作用及其机制进行综述。The gut microbiome actively regulates host immunity,digestive processes,and the function of the intestinal endocrine system.Additionally,it modulates host neural signal transmission and nutrient metabolism through metabolite generation.Vascular calcification involves the deposition of calcium phosphate in blood vessel walls,secondary to metabolic disorders such as chronic kidney disease,atherosclerosis,diabetes,and osteoporosis.Recent research spanning the past two decades has indicated a close correlation between shifts in the composition and functionality of the gut microbiota,along with its metabolites,and the onset of metabolic disease-related vascular calcification.This paper presents a comprehensive review of the roles and mechanisms of the gut microbiota in this context.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.179