A comparative analysis of EQ-5D-5L general population norms across 23 countries:Gender and age disparities  

作　　者：Zitong Wang Nan Luo Pei Wang 

机构地区：[1]School of Public Health,Fudan University,Shanghai,200032,China [2]Key Lab of Health Technology Assessment,National Health Commission of the People's Republic of China,Fudan University,Shanghai,200032,China [3]National University of Singapore,Singapore,117597,Singapore

出　　处：《Pharmacoeconomics and Policy》2025年第1期5-14,共10页药物经济与政策(英文)

摘　　要：To explore health disparities among populations across countries,the study compared the 5-level EuroQol 5-dimensions version(EQ-5D-5L)population norms across 23 countries and identified differences in EQ-5D health problems,health utility score(HUS),and EQ-5D visual analog scale(VAS)score by country,gender,and age.Guided by the Preferred Reporting Items for Systematic reviews and Meta-analyses(PRISMA)systematic review and meta-analysis guidelines,a systematic literature search was conducted in databases of PubMed,Web of Science,MEDLINE,and EMBASE(until January 2025)to extract country,gender,and age-specific population norms reporting ceiling effect,EQ-5D-5L health problems,HUS,and EQ VAS scores.Only nationally representative norms derived from the latest population data were included in this study.The norms revealed significant variation in ceiling effect health problems and health-related quality of life(HRQoL)metrics.The ceiling effect varied substantially,with higher effects in Asian countries,reflecting cultural and demographic influences.Pain/discomfort(PD)was the most frequently reported problem,while self-care(SC)was the least common across all countries.Mean HUS and EQ VAS scores of the norms were 0.897 and 79.0,respectively,with notable regional,gender,and age-related differences.Females generally reported lower HRQoL than males,though exceptions were observed in specific dimensions and countries.This study compared the EQ-5D-5L population norms globally,providing valuable insights for HRQoL assessments,health policy making,and economic evaluations.The results highlighted the importance of considering cultural and demographic factors when interpreting HRQoL data.

关 键 词：Population norms EQ-5D-5L Health-related quality of life 

分 类 号：O17[理学—数学]