有机络合Cu(Ⅱ)介导过二硫酸盐降解氧氟沙星的研究  

Degradation of ofloxacin by organic complex Cu(Ⅱ)mediated peroxydisulfate

作　　者：张笑萌 周润生 周磊 修光利[1,2] ZHANG Xiaomeng;ZHOU Runsheng;ZHOU Lei;XIU Guangli(State Environmental Protection Key Lab of Environmental Risk Assessment and Control on Chemical Processes,School of Resources and Environmental Engineering,East China University of Science and Technology,Shanghai 200237;Shanghai Academy of Pollution Control and Ecological Security,Shanghai 200092)

机构地区：[1]华东理工大学资源与环境工程学院,国家环境保护化工过程环境风险评价与控制重点实验室,上海200237 [2]上海污染控制与生态安全研究院,上海200092

出　　处：《环境污染与防治》2025年第3期36-41,共6页Environmental Pollution & Control

摘　　要：氧氟沙星(OFX)是最常用的氟喹诺酮类抗生素(FQs)之一,在水体中检出率高,对生态安全和人体健康造成严重危害。水体中广泛且稳定存在的过渡金属离子Cu(Ⅱ)对基于过二硫酸盐(PDS)的高级氧化技术有一定影响,但其机制尚不明确。重点研究了Cu(Ⅱ)介导PDS体系降解OFX的过程,发现在6.0 mmol/L Cu(Ⅱ)和6 mmol/L PDS共存条件下,2 min内OFX的降解率可达到50.78%。淬灭实验表明,Cu(Ⅱ)介导的PDS体系降解受到了羟基自由基(·OH)、硫酸根自由基(SO_(4)^(-)·)的作用。产物鉴定结果表明,有机络合Cu(Ⅱ)介导作用下,OFX可通过羟基化、脱羧基和去甲基化3条路径发生转化。毒性鉴定结果表明,OFX的6种降解产物中4种属于无毒范围。Ofloxacin(OFX)is one of the most commonly used Fluoroquinolones(FQs)with a high detection rate in water,causing serious harm to ecological safety and human health.Transition metal ion Cu(Ⅱ),which is widely and stably present in water,has a certain impact on advanced oxidation process based on peroxydisulfate(PDS),but its mechanism is still unclear.The degradation of OFX by Cu(Ⅱ)-mediated PDS system was focused on.It was found that under the coexistence of 6.0 mmol/L Cu(Ⅱ)and 6 mmol/L PDS,the degradation rate of OFX could reach 50.78% within 2 minutes.The quenching experiment showed that the degradation of PDS system mediated by Cu(Ⅱ)was affected by hydroxyl radicals(·OH)and sulfate radicals(SO_(4)^(-)·).The product identification results showed that under the mediation of organic complex Cu(Ⅱ),OFX could be transformed through three pathways:hydroxylation,decarboxylation and demethylation.The toxicity identification results showed that 4 out of 6 degradation products of OFX belonged to the non-toxic range.

关 键 词：过二硫酸盐 氧氟沙星 Cu(Ⅱ) 高级氧化法 络合物 

分 类 号：R28[医药卫生—中药学]