杏芎注射液联合美托洛尔治疗对冠心病心绞痛患者心绞痛发作情况的影响  

Effect of Xingxiong injection combined with metoprolol on angina pectoris in patients with coronary heart disease

作　　者：刘庆力 杨丽[1] 牛少琼 刘思蕾 Liu Qingli;Yang Li;Niu Shaoqiong;Liu Silei(The First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan 471000,China)

机构地区：[1]河南科技大学第一附属医院,河南洛阳471000

出　　处：《辽宁医学杂志》2025年第1期5-8,共4页Medical Journal of Liaoning

基　　金：河南省卫生健康委员会(编号:LHGJ20210584)。

摘　　要：目的探究杏芎注射液联合美托洛尔治疗对冠心病心绞痛患者心绞痛发作情况的影响。方法按照抽签法将我院2022年3月至2024年5月确诊的60例冠心病心绞痛分为对照组(美托洛尔治疗,n=30)和研究组(杏芎注射液+美托洛尔治疗,n=30)。评估两组患者临床疗效、心绞痛发作情况、炎性因子水平、心功能、不良反应发生情况等指标的变化差异。结果相较于对照组(73.33%),研究组临床总有效率(93.33%)偏高(P<0.05);相较于治疗前,治疗14d后研究组心绞痛发作情况、各炎性因子水平、心功能各指标水平均优于对照组(P<0.05),而不良反应发生率无差异(P>0.05)。结论冠心病心绞痛患者经过14d杏芎注射液+美托洛尔联合治疗后,其心绞痛发作情况、炎性因子水平、心功能均得到明显的改善,且安全性相对较高,不易增加不良反应发生风险,疗效显著。Objective To explore the effect of Xingxiong injection combined with metoprolol on angina pectoris in patients with coronary heart disease.Methods According to the lottery method,60 cases of angina pectoris diagnosed in our hospital from March 2022 to May 2024 were divided into control group(metoprolol treatment,n=30)and study group(Xingqin injection+metoprolol treatment,n=30).The clinical efficacy,angina attack situation,inflammatory factor level,cardiac function,adverse reactions and other indicators of the two groups were evaluated.Results Compared with the control group(73.33%),the total clinical effective rate of the study group(93.33%)was higher(P<0.05).Compared with before treatment,the angina pectoris attack,inflammatory factors and cardiac function indexes of the study group after 14 days of treatment were better than those of the control group(P<0.05),while the incidence of adverse reactions was not different(P>0.05).Conclusion After 14 days of combined treatment with Xingqin injection and metoprolol,angina pectoris in patients with coronary heart disease was significantly improved,the level of inflammatory factors and cardiac function,and the safety was relatively high,which was not easy to increase the risk of adverse reactions.

关 键 词：杏芎注射液 美托洛尔 冠心病心绞痛 心绞痛发作情况 炎性因子水平 心功能 

分 类 号：R54[医药卫生—心血管疾病]