立体定向下颅内血肿清除术对老年急性脑出血患者的效果及其NSE、GFAP、S100B水平的影响  

Effect of stereotactic intracranial hematoma removal on elderly patients with acute ICH and the effect of NSE,GFAP,and S100B levels

作　　者：张海龙 李浩 孙勇 Zhang Hailong;Li Hao;Sun Yong(Xinyang City Central Hospital,Henan,Xinyang 464099)

机构地区：[1]信阳市中心医院,河南信阳464099

出　　处：《辽宁医学杂志》2025年第1期53-56,共4页Medical Journal of Liaoning

摘　　要：目的探讨立体定向下颅内血肿清除术对老年急性脑出血(AICH)患者的效果及其NSE、GFAP及S100B水平的影响。方法将2021年1月至2023年1月于该院就医的老年AICH患者按照随机数字表法将其分为对照组(40例)、观察组(40例),对照组给予传统小骨窗清除术,观察组给予立体定向下血肿清除术,观察两组患者美国脑卒中评分量表(NIHSS)、炎症因子水平、神经损伤及预后情况。结果术后1个月,观察组患者NIHSS评分低于对照组;观察组IL-10水平高于对照组,IL-18水平低于对照组;观察组NES、GFAP、S100B水平均低于对照组,观察组GOS评分高于对照组,差异均有统计学意义(P<0.05)。结论对老年AICH患者采用立体定向下颅内血肿清除术可有效改善患者神经功能,减少神经损伤,降低炎症因子水平,改善预后。Objective To investigate the effect of intracranial hematoma removal on elderly patients with acute cerebral hemorrhage(AICH)and the effect of NSE,GFAP and S100B levels.Methods Elderly AICH patients in the hospital from January 2021 to January 2023 were divided into control group(40 cases),observation group(40 cases),the control group gave traditional small bone window removal,observation group gave stereotactic hematoma removal,and observed the American stroke score scale(NIHSS),inflammatory factors,and neurological damage and prognosis.Results One month after surgery,patients had lower NIHSS scores than the control group;IL-10 level was higher than the control group,IL-18 level was lower than the control group;NES,GFAP,and S100B levels were all lower than the control group,and the GOS score was higher than the control group,all statistically significant(P<0.05).Conclusion The removal of intracranial intracranial hematoma in elderly AICH patients can effectively improve nerve function,reduce nerve damage,reduce inflammatory factor level and improve prognosis.

关 键 词：立体定向下颅内血肿清除术 老年急性脑出血 神经功能 神经损伤 

分 类 号：R651.1[医药卫生—外科学]