基于锥形束CT的肿瘤滋养动脉检测软件在经肝动脉化疗栓塞术的临床应用价值  

Clinical application value of the cone beam CT software in detection of tumor-feeding arteries in transarterial chemoembolization

作　　者：林颖 安睿 徐健 LIN Ying;AN Rui;XU Jian(Interventional Surgery Center,Xijing Hospital,the Air Force Military Medical University,Xi’an 710032,China;Department of Epidemiology and Biostatistics School of Public Health,Xi’an Jiaotong University Health Science Center,Xi’an 710061,China;Department of Radiology,Xijing Hospital,the Air Force Military Medical University,Xi’an 710032,China)

机构地区：[1]空军军医大学西京医院介入手术中心,陕西西安710032 [2]西安交通大学公共卫生学院流行病与卫生统计学系,陕西西安710061 [3]空军军医大学西京医院放射诊断科,陕西西安710032

出　　处：《实用放射学杂志》2025年第1期110-113,共4页Journal of Practical Radiology

摘　　要：目的探讨基于锥形束CT(CBCT)肿瘤滋养动脉检测软件FPFL在经肝动脉化疗栓塞术(TACE)中的临床应用价值。方法回顾性分析行TACE治疗的120例患者,依据患者TACE中是否使用肿瘤滋养动脉检测软件FPFL分为FPFL组和传统治疗组。采用倾向得分匹配(PSM)方法对2组患者按照1︰1的比例进行匹配,匹配变量包括年龄、性别、病灶数量、美国东部肿瘤协作组(ECOG)评分、肿瘤最大径和甲胎蛋白(AFP)值。最终,FPFL组和传统治疗组共11对患者匹配成功;分析2组患者术中临床资料的差异。结果术者在术中2组患者共确认38个肿瘤,识别、确认92支肿瘤供血动脉,其中传统治疗组术中识别准确性为93%;FPFL组识别准确性为100%;2组患者的技术成功率均为100%;与传统治疗组相比,FPFL组中透视曝光时间降低28%,总的空气比释动能降低37.12%,剂量面积乘积(DAP)值降低52.38%,数字减影血管造影(DSA)序列数减少52.63%,碘对比剂用量减少39.26%,手术时间缩短40.49%。结论FPFL软件能够有效提高肿瘤滋养动脉的识别和确认,显著降低手术时间、碘对比剂用量和辐射剂量等,优化手术流程。Objective To explore the clinical application value of software in detection of tumor-feeding arteries FPFL based on cone beam computed tomography(CBCT)in the transarterial chemoembolization(TACE).Methods A retrospective analysis was conducted on 120 patients who underwent TACE treatment.According to whether the tumor-feeding arteries detection software FPFL was used during TACE procedures,the patients were divided into FPFL group and traditional treatment group.The propensity score matching(PSM)method was used to match the two groups in a ratio of 1︰1,with the matching variables including age,gender,number of lesions,Eastern Cooperative Oncology Group(ECOG)score,maximum tumor diameter,and alpha-fetoprotein(AFP)value.Ultimately,a total of 11 pairs of patients were successfully matched between the FPFL group and the traditional treatment group,and then the differences of intraoperative clinical data between the two groups were analyzed.Results The surgeon identified a total of 38 tumors in both groups of patients during the operation,and then 92 tumor supplying arteries were recognized and confirmed.The identification accuracy was 93%for the traditional treatment group and 100%for the FPFL group.The technical success rates of both groups of patients were 100%.Compared with the traditional treatment group,the FPFL group had the reduction of 28%in fluoroscopy exposure time,37.12%in total air release energy,52.38%in dose-area product(DAP)value,52.63%in digital subtraction angiography(DSA)sequence number,39.26%in iodine contrast agent dosage,and 40.49%in surgical time.Conclusion The FPFL software can effectively improve the identification and confirmation of tumor-feeding arteries,significantly reduce the surgical time,iodine contrast agent dosage and radiation dose,and optimizes the surgical process.

关 键 词：经肝动脉化疗栓塞术 锥形束CT 辐射剂量 肿瘤滋养动脉 

分 类 号：R815[医药卫生—放射医学] R814.42[医药卫生—临床医学]