广东地区反流性食管炎发病情况研究  

A study on the incidence of reflux esophagitis in the Guangdong region

作　　者：张思乐 康旖敏 徐钦涌 许少芬 侯政昆[3] ZHANG Sile;KANG Yimin;XU Qinyong;XU Shaofen;HOU Zhengkun(The First Clinical School of Guangzhou University of Chinese Medicine,Guangzhou,510405,China;Department of Traditional Chinese Medicine,Binhaiwan Central Hospital of Dongguan;Department of Gastroenterology,the First Affiliated Hospital of Guangzhou University of Chinese Medicine)

机构地区：[1]广州中医药大学第一临床医学院,广州510405 [2]东莞市滨海湾中心医院中医科 [3]广州中医药大学第一附属医院脾胃病科

出　　处：《中国中西医结合消化杂志》2025年第1期1-5,12,共6页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：广东省中医药信息化重点实验室项目(No:2021603);广州中医药大学第一附属医院中青年骨干人才培育项目[No:中医一院(2023)186号]。

摘　　要：目的:分析广东地区胃镜检出反流性食管炎(reflux esophagitis,RE)的时间分布和合并疾病分布情况。方法:分析2014年1月1日—2024年1月1日于广州中医药大学第一附属医院行胃镜检查的患者中RE的检出率,对病例资料进行回顾性分析,提取性别、年龄、检查日期和结论,然后对检查结论进行结构化信息提取。结果:RE检出率为9.87%。RE分级为A级11595例(73.9%),B级2976例(19.0%),C级860例(5.5%),D级258例(1.6%)。其中男11515例(73.4%),女4174例(26.6%),男女比例2.8∶1.0。夏季检出病例数最多,为4097例(26.1%),四季间检出率比较差异有统计学意义(P<0.05)。在检出节气方面,RE的发病节气高峰点为寒露,相对高峰期为惊蛰至立夏。在合并疾病方面,合并最多的是慢性浅表性胃炎伴糜烂,共6454例(41.14%),合并消化性溃疡中以十二指肠溃疡2513例(16.02%)为多,合并十二指肠炎2349例(14.97%)。结论:广东地区RE检出以青中年、A级、夏季人数较多,寒露为发病高峰点,相对高峰期为惊蛰至立夏;性别上男性多于女性;合并疾病种类较多,以慢性浅表性胃炎伴糜烂、十二指肠炎、十二指肠溃疡、胃息肉多见。Objective To analyze the temporal distribution and comorbidities of reflux esophagitis(RE)detected by gastroscopy in the Guangdong region.Methods We conducted a retrospective analysis of patients who underwent gastroscopy at the First Affiliated Hospital of Guangzhou University of Chinese Medicine between January 2014 and January 2024.We calculated the detection rate of RE and extracted case data,including gender,age,examination date,and diagnostic conclusions.We applied a structured data extraction method to analyze the examination results.Results The overall detection rate of RE was 9.87%.The distribution of RE according to the Los Angeles(LA)classification was as follows:11595 cases(73.9%)in A,2976 cases(19.0%)in B,860 cases(5.5%)in C,and 258 cases(1.6%)in D.Of these,11515 cases were male(73.4%)and 4174 were female(26.6%),with a male-to-female ratio of 2.8∶1.0.The highest number of cases occurred during the summer,with 4097 cases(26.1%),demonstrating statistically significant seasonal variation(P<0.05).The peak incidence of RE was observed during the Cold Dew solar term,with a relative increase from the Awakening of Insects solar term to the Beginning of Summer solar term.The most common comorbidity was chronic superficial gastritis with erosion,found in 6454 cases(41.14%).Other common comorbidities included duodenal ulcers(2513 cases,16.02%)and duodenitis(2349 cases,14.97%).Conclusion In Guangdong,RE is commonly detected in younger and middle-aged individuals,with a higher prevalence of A grade.The peak incidence occurs in the summer and shows a seasonal peak during the Cold Dew solar term,with a relative peak from the Awakening of Insects to the Beginning of Summer.Males are more frequently affected than females.Common comorbidities include chronic superficial gastritis with erosion,duodenitis,and duodenal ulcers.

关 键 词：反流性食管炎 内镜术 时间分布 疾病分布 

分 类 号：R256.3[医药卫生—中医内科学]