基于磷氧键断裂的氟离子荧光探针  

Fluoride fluorescence probe based on phosphorus-oxygen bond breakage

作　　者：郇凤 鲁超 Huan Feng;Lu Chao(Fujian Provincial Key Laboratory of Featured Materials in Biochemical Industry,Fujian Province University Key Laboratory of Green Energy and Environment Catalysis,College of Chemistry and Materials,Ningde Normal University,Ningde 352000,China;Ningde Marine Environmental Monitoring Center,Ningde 352000,China;Key Laboratory of Marine Ecological Monitoring and Restoration Technologies,Ministry of Natural Resources,Shanghai 200137,China)

机构地区：[1]福建省特色生物化工材料重点实验室,绿色能源与环境催化福建省高校重点实验室,宁德师范学院化学与材料学院,宁德352000 [2]自然资源部宁德海洋中心,宁德352000 [3]自然资源部海洋生态监测与修复技术重点实验室,上海200137

出　　处：《分析试验室》2025年第2期211-215,共5页Chinese Journal of Analysis Laboratory

基　　金：福建省科技厅项目(2022J05267);宁德师范学院科研项目(2019Y02);福建省教育厅科技项目(JAT200691)资助。

摘　　要：设计了以吡啶基噻唑为荧光基团,二甲基硫代磷酰氯为氟离子(F-)识别基团的荧光探针P1。该探针与F-结合后,溶液颜色由无色变为浅黄色,在365 nm紫外灯照射下颜色由蓝色变为绿色,能够实现对F-的裸眼识别。荧光光谱分析表明,探针与F-作用后,在399 nm处的强荧光峰明显减弱,表明该探针是“关闭型”荧光探针。该探针用于检测F-,荧光强度与F-浓度在10~180μmol/L范围内呈较好的线性关系,具有较好的选择性和抗干扰性。A fluorescent probe P1 was designed with pyridinylthiazole as the fluorescent group and dimethyl thiophosphoryl chloride as the fluoride ion recognition group.The color of the solution changes from colorless to light yellow after interacting with fluoride ion,and from blue to green under 365 nm UV-light,which enables recognition of fluoride ion by naked eyes.In fluorescence spectrum,the strong fluorescence peak at 399 nm is significantly weakened after the probe interacting with fluoride ion,indicating the probe P1 is a"turn-off"type fluorescence probe.The probe P1 has strong selectivity and anti-interference ability for fluoride ion,and there is a good linear relationship between fluorescence intensity and fluoride ion concentration in the range of 10-180μmol/L.

关 键 词：氟离子 荧光探针 磷氧键断裂 反应型 

分 类 号：O657.31[理学—分析化学]