盆底超声参数联合血生化指标对产后早期压力性尿失禁的诊断效能  

Diagnostic Efficacy of Pelvic Floor Ultrasound Parameters Combined with Blood Biochemical Indicators for Early Postpartum Stress Urinary Incontinence

作　　者：周锋 李晓彦 岳丽 康华 Zhou Feng;Li Xiaoyan;Yue Li;Kang Hua(Department of Ultrasound Medicine,Nanyang First People's Hospital Affiliated to Henan University,Nanyang,Henan 473003,China)

机构地区：[1]河南大学附属南阳市第一人民医院超声医学科,河南省南阳市473003

出　　处：《中国超声医学杂志》2025年第3期308-312,共5页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 探讨盆底超声参数联合血生化指标对产后早期压力性尿失禁(SUI)的诊断效能。方法 回顾性分析182例产妇临床资料,依据产后6~8周是否并发SUI分为SUI组、非SUI组。收集比较两组基线资料、二维与三维盆底超声参数、血生化指标[弹性蛋白酶抑制因子(elafin)、骨桥蛋白(OPN)、松弛素(RLX)]水平。分析盆底超声参数、血生化指标对产后早期SUI的诊断性能。结果 Logistic回归分析发现,年龄、本次分娩方式、膀胱颈漏斗形成、膀胱颈移动度与血清OPN、RLX为产后早期并发SUI危险因素,血清elafin为保护因素(P<0.05)。绘制受试者工作特征(ROC)曲线显示,盆底超声参数、血生化指标两者联合诊断模型诊断产后早期并发SUI的曲线下面积(AUC)为0.970,高于盆底超声参数、血生化指标单一诊断模型(P<0.05)。决策曲线显示,当阈概率值在0.1~0.7时两者联合诊断模型的临床净获益大于盆底超声参数、血生化指标单一诊断模型。结论 盆底超声参数联合血生化指标对产后早期SUI具有良好诊断价值。Objective To investigate the diagnostic efficacy of pelvic floor ultrasound parameters combined with blood biochemical indicators for early postpartum stress urinary incontinence(SUI).Methods Clinical data of 182 postpartum women were retrospectively analyzed.Patients were divided into the SUI group and the non-SUI group based on whether they developed SUI at 6-8 weeks postpartum.Baseline characteristics,two-dimensional and three-dimensional pelvic floor ultrasound parameters,and blood biochemical indicators[elastase inhibitor(elafin),os-teopontin(OPN),and relaxin(RLX)] were collected and compared between the two groups.The diagnostic perform-ance of pelvic floor ultrasound parameters and blood biochemical indicators for early postpartum SUI were analyzed.Results Logistic regression analysis found that age,current delivery mode,bladder neck funneling,bladder neck mobility,serum OPN,and RLX were risk factors for early postpartum SUI,while serum elafin was a protective fac-tor(P<0.05).Receiver operating characteristic(ROC)curve analysis showed that the area under the curve(AUC)of the combined diagnostic model was O.970,which was higher than that of single diagnostic models using either pel-vic floor ultrasound parameters or blood biochemical indicators alone(P<0.05).Decision curve analysis showed that when the threshold probability was between O.1-O.7,the combined diagnostic model demonstrated greater clinical net benefit than single diagnostic models.Conclusions The combination of pelvic floor ultrasound parameters and blood biochemical indicators shows good diagnostic value for early postpartum SUI.

关 键 词：盆底超声参数 血生化指标 压力性尿失禁 

分 类 号：R445.1[医药卫生—影像医学与核医学] R711.59[医药卫生—诊断学]