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作 者:牛可雄 李天刚[1] 燕志恒 杨琼宇 Niu Kexiong;Li Tiangang;Yan Zhiheng;Yang Qiongyu(Department of Ultrasound,Gansu Provincial Maternity and Child-Care Hospital,Lanzhou 730050,China)
机构地区:[1]甘肃省妇幼保健院(甘肃省中心医院)超声医学中心,兰州市730050
出 处:《中国超声医学杂志》2025年第3期338-341,共4页Chinese Journal of Ultrasound in Medicine
基 金:甘肃省自然科学基金(No.23JRRA1747)。
摘 要:目的 探讨弹性成像与超声造影结合的多模态评估在子宫腺肌瘤微波消融疗效评估中的应用价值,旨在提供病灶硬度和血流变化的综合信息,以优化治疗效果并降低复发风险。方法 本研究纳入26例子宫腺肌瘤患者,采用弹性成像和超声造影在术前、术后1 d和术后6个月进行评估,收集弹性成像参数(剪切波速度、杨氏模量)和超声造影参数(增强特征),分析消融区的大小、边界特征和残留组织情况。结果 术后腺肌瘤体积显著缩小,剪切波速度和杨氏模量显著增加,显示组织硬度变化;超声造影显示多数病灶动脉期快速增强、静脉期迅速消退。随访6个月后,多数患者病灶血流减少,症状缓解,少数病例出现残留血流信号,提示复发可能。结论 弹性成像与超声造影结合的多模态评估能有效反映微波消融效果及腺肌瘤复发风险,有助于个体化治疗方案的制订。Objective To explore the value of multimodal assessment combining elastography and ultrasonogra phy in evaluating the efficacy of microwave ablation of uterine adenomyomas,to provide comprehensive information on the changes in lesion stiffness and blood flow,and to optimize the therapeutic efficacy and reduce the risk of recurrence.Methods Twenty-six patients with adenomyomas of the uterus were included in this study and were evaluated using elastography and ultrasonography preoperatively,1 day postoperatively,and 6 months postoperatively.Elastographic parameters(shear wave velocity,Young's modulus)and ultrasonographic parameters(enhancement features)were collected to analyze the size of the ablation zone,boundary features,and residual tissue.Results Postoperatively,adenomyoma volume was significantly reduced,and shear wave velocity and Young's modulus were significantly increased,showing changes in tissue stiffness;ultrasonography showed rapid enhancement in the arterial phase and rapid regression in the venous phase in most lesions.After 6 months of follow-up,most patients had reduced blood flow in the lesions and symptomatic relief,while a few cases showed residual blood flow signals,suggesting the possibility of recurrence.Conclusions Multimodal assessment by combining elastography and ultrasonography can effectively reflect the effect of microwave ablation and the risk of recurrence of adenomyoma,which is helpful for the development of individualized treatment plan.
关 键 词:子宫腺肌瘤 微波消融 弹性成像 超声造影 多模态评估 复发风险 个体化治疗
分 类 号:R445.1[医药卫生—影像医学与核医学] R737.33[医药卫生—诊断学]
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