终末期心力衰竭患者左心室辅助装置植入后并发缺血性脑卒中的研究进展  

Research progress on ischemic stroke complicating left ventricular assist device implantation in patients with end-stage heart failure

作　　者：王端步 蒋艳 包辉 Wang Duanbu;Jiang Yan;Bao Hui(Sanmen People's Hospital,317100 Taizhou,China)

机构地区：[1]浙江省三门县人民医院,台州317100

出　　处：《心脑血管病防治》2025年第2期40-44,47,共6页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

摘　　要：左心室辅助装置的应用改变了终末期心力衰竭患者的治疗方式,使更多患者能够存活到心脏移植,并为那些无法接受移植的患者提供更好的生活质量和更长的生存期。虽然这一技术带来了显著优势,并且设备的技术不断改进,但左心室辅助装置仍然存在与神经系统并发症相关的风险,其中缺血性脑卒中的发生率最高。尽管目前尚缺乏针对此并发症的明确评估和治疗指南,但及早识别和及时干预可能有助于改善患者神经系统的不良预后。本综述提供了植入左心室辅助装置患者并发缺血性脑卒中病理生理、危险因素、预防和治疗方面的相关信息,以期为临床实践提供帮助。The application of left ventricular assist device(LVAD)has transformed the treatment of patients with end-stage heart failure,enabling more patients to survive until heart transplantation and providing better quality of life and extended survival for those who are not eligible for transplantation.Although this technology has brought significant benefits and the technology of the equipment is constantly improving,the use of LVAD is still associated with the risk of neurological complications,among which ischemic stroke has the highest incidence.Despite the lack of clear guidelines for the assessment and treatment of this complication,early identification and timely intervention may help improve the neurological outcomes in these patients.This review provides information on the pathophysiology,risk factors,prevention and treatment of ischemic stroke in patients with LVAD implantation,aiming to assist clinical practice.

关 键 词：左心室辅助装置 缺血性脑卒中 抗凝治疗 

分 类 号：R54[医药卫生—心血管疾病]