心室辅助装置的发展历程与未来展望  

The evolution of ventricular assist devices and future perspectives

作　　者：李盛华 柳梅 李涵泺 雷雅岚 尚小珂 LI Sheng-hua;LIU Mei;LI Han-luo;LEI Ya-lan;SHANG Xiao-ke(Sino-German Biomedical Center-Cardiac Dynamics and Assistive Technology Laboratory,School of Life and Health Sciences,Hubei University of Technology,Wuhan 430068,China;Department of Cardiovascular Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]湖北工业大学生命科学与健康工程学院,中德生物医学中心-心脏动力与辅助技术实验室,湖北武汉430068 [2]华中科技大学同济医学院附属协和医院心脏大血管外科,湖北武汉430022

出　　处：《中国介入心脏病学杂志》2025年第3期170-175,共6页Chinese Journal of Interventional Cardiology

基　　金：国家重点研发计划项目(2023YFC2706203);武汉市科技局科技成果转化重点项目(2024030803010189);武汉市东湖高新“揭榜挂帅”项目(2024KJB345)。

摘　　要：心室辅助装置(VAD)作为治疗终末期心力衰竭的重要手段,经历了从气动搏动式血泵到连续流离心泵的技术革新。本文详细介绍了HeartMateⅢ、EVAHEART 2、Heart Con等多款VAD的产品信息,第一代VAD虽并发症频发,但为后续发展奠定了基础;第二代VAD显著改善了患者预后,但仍存在心室塌陷的风险;第三代VAD体积小,采用无接触悬浮技术显著提升了耐用性和血液相容性。未来VAD将更好地致力于模拟天然心脏的生理功能,通过增强搏动性、延长设备寿命等措施,为心力衰竭患者提供更多的治疗选择。Ventricular assist devices(VADs) have emerged as a pivotal therapeutic option for end-stage heart failure,undergoing significant technological advancements from pneumatic membrane pumps to continuous-flow centrifugal pumps.This review provides a detailed overview of several VAD models,including HeartMate Ⅲ,EVAHEART 2,and Heart Con.The initial generation of VADs established a foundation for subsequent developments,despite the occurrence of frequent complications.The second generation of VADs demonstrated a notable improvement in patient prognosis but carried the risk of ventricular collapse.The third generation of VADs represents a further reduction in size,incorporating magnetic levitation technology to enhance durability and blood compatibility.In the future,the development of VADs will focus on better emulating the physiological function of the native heart,improving pulsatility,and extending device longevity.As technology advances,VADs are expected to offer heart failure patients with a greater range of treatment options and a higher quality of life.

关 键 词：心室辅助装置 心力衰竭 人工心脏 HeartMateⅢ EVAHEART 2 Heart Con 

分 类 号：R5[医药卫生—内科学]