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作 者:黄华杰 HUANG Huajie(Department of General Surgery,Renhuai People's Hospital,Zunyi,Guizhou 564507,China)
出 处:《医药前沿》2025年第8期51-53,56,共4页Journal of Frontiers of Medicine
摘 要:目的观察内镜下逆行胰胆管造影术(ERCP)联合腹腔镜下胆囊切除术(LC)微创治疗胆囊结石合并胆总管结石的临床效果。方法选取2022年3月—2023年3月仁怀市人民医院治疗的胆囊结石合并胆总管结石患者80例,采用随机数字表法将患者分为试验组40例和对照组40例。对照组采用传统的开腹手术治疗,试验组采用ERCP联合LC微创治疗,比较两组手术指标、炎症水平、不良反应发生率、一次结石取尽率及复发率。结果试验组术后排气时间、住院时间均短于对照组,术中出血量少于对照组,并发症总发生率低于对照组(P<0.05);两组术后白细胞介素-6(IL-6)、白细胞计数(WBC)均升高,但试验组IL-6、WBC水平低于对照组(P<0.05);两组一次结石取尽率、复发率比较,差异无统计学意义(P>0.05)。结论ERCP联合LC微创治疗胆囊结石合并胆总管结石疗效良好,有利于提高取石效果,减少并发症发生,改善炎症水平,缩短患者术后恢复时间。Objective To observe the clinical effect of endoscopic retrograde cholangiopancreatography(ERCP)combined with laparoscopic cholecystectomy(LC)in minimally invasive treatment of cholecystolithiasis and choledocholithiasis.Methods A total of 80 patients with cholecystolithiasis and choledocholithiasis treated in Renhuai People's Hospital from March 2022 to March 2023 were selected and divided into experimental group(40 cases)and control group(40 cases)by random number table method.The control group was treated with traditional open surgery,and the experimental group was treated with ERCP combined with LC minimally invasive treatment,the surgical indicators,inflammation level,incidence of adverse reactions,one-time stone removal rate and recurrence rate were compared between the two groups.Results The postoperative exhaust time and hospitalization time of the experimental group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,and the total incidence of complications was lower than that of the control group(P<0.05);the levels of interleukin-6(IL-6)and white blood cell count(WBC)in the two groups increased after operation,but the levels of IL-6 and WBC in the experimental group were lower than those in the control group(P<0.05);there was no significant difference in the one-time stone removal rate and recurrence rate between the two groups(P>0.05).Conclusions ERCP combined with LC minimally invasive treatment for patients with cholecystolithiasis and choledocholithiasis has a good effect,which is conducive to improving the effect of stone removal,reducing complications,improving the level of inflammation,and shortening the postoperative recovery time of patients.
关 键 词:内镜下逆行胰胆管造影术 腹腔镜下胆囊切除术 胆囊结石 胆总管结石 临床效果
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