基于营养评估的个性化营养干预在鼻咽癌放化疗患者中的应用效果  

Application effect of personalized nutrition intervention based on nutrition assessment in patients with nasopharyngeal carcinoma undergoing radiotherapy and chemotherapy

作　　者：钟伟媚 ZHONG Weimei(Department of Radiotherapy,Sun Yat-sen University Cancer Center,Guangzhou,Guangdong 510000,China)

机构地区：[1]中山大学肿瘤防治中心放疗科,广东广州510000

出　　处：《医药前沿》2025年第8期95-98,共4页Journal of Frontiers of Medicine

摘　　要：目的 观察基于营养评估的个性化营养干预在鼻咽癌放化疗患者中的应用效果。方法 回顾性分析2022年1月—2023年2月中山大学肿瘤防治中心收治的134例鼻咽癌放化疗患者的临床资料,根据不同护理方法分为观察组(n=70)和对照组(n=64)。对照组采用常规护理,观察组增加基于营养评估的个性化营养干预。比较两组营养状态、负性情绪、生活质量及治疗依从性。结果 护理后,两组血红蛋白(Hb)、白蛋白(Alb)、转铁蛋白(TRF)、体重指数(BMI)水平均高于护理前,前白蛋白(PAB)水平、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分及欧洲癌症治疗研究组织生命质量测定量表(EORTC-QLQ-C30)各维度评分均低于护理前,且观察组Hb、Alb、TRF、BMI水平高于对照组,PAB水平、SAS评分、SDS评分及EORTC-QLQ-C30各维度评分低于对照组(P<0.05);观察组治疗依从性高于对照组(P<0.05)。结论 基于营养评估的个性化营养干预可以提升鼻咽癌放化疗患者的营养水平,减轻焦虑、抑郁情绪,提高其生活质量和治疗依从性。Objective To observe the application effect of personalized nutrition assessment based on nutritional evaluation in patients with nasopharyngeal carcinoma undergoing radiotherapy and chemotherapy.Methods The clinical data of 134 patients with nasopharyngeal carcinoma treated by radiotherapy and chemotherapy in Sun Yat-sen University Cancer Center from January 2022 to February 2023 were retrospectively analyzed,and they were divided into observation group(n=70)and control group(n=64)according to different nursing methods.The control group received routine nursing,and the observation group added individualized nutrition intervention.The nutritional status,negative mood,quality of life and treatment compliance were compared between the two groups.Results After nursing,the levels of hemoglobin(Hb),albumin(Alb),transferrin(TRF)and body mass index(BMI)in both groups were higher than before nursing,prealbumin(PAB),Self-Rating Anxiety Scale(SAS)scores,Self-Rating Depression Scale(SDS)scores and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30(EORTC-QLQ-C30)scores were lower than before nursing,and the levels of Hb,Alb,TRF and BMI in the observation group were higher than those in the control group,the PAB level,SAS and SDS scores,EORTC-QLQ-C30 scores were lower than those in the control group(P<0.05);the treatment compliance of the observation group was higher than that of the control group(P<0.05).Conclusions Individualized nutrition intervention based on nutritional evaluation can improve the nutritional level of patients with nasopharyngeal carcinoma undergoing radiotherapy and chemotherapy,reduce anxiety and depression,improve their quality of life and treatment compliance.

关 键 词：鼻咽癌 放疗 化疗 营养评估 个性化营养干预 营养状态 

分 类 号：R473[医药卫生—护理学]