某院重症监护室药物混合输注的相容性调查分析及优化策略  

Investigation and Optimization Strategy on the Compatibility of Drug Mixed Infusions in ICU of A Hospital

作　　者：范理菊 彭帅宁 赵晓玉[1,2] 安静 董占军[1,2] FAN Liju;PENG Shuaining;ZHAO Xiaoyu;AN Jing;DONG Zhanjun(Department of Pharmacy,Hebei General Hospital,Shijiazhuang 050051,China;Hebei Key Laboratory of Clinical Pharmacy,Shijiazhuang 050051,China)

机构地区：[1]河北省人民医院药学部,石家庄050051 [2]河北省临床药学重点实验室,石家庄050051

出　　处：《医药导报》2025年第4期656-661,共6页Herald of Medicine

基　　金：河北省医学科学研究课题计划(20230396)。

摘　　要：目的评估河北省人民医院重症监护室(ICU)中常用静脉药物混合输注的相容性,并提出优化策略。方法调取河北省人民医院ICU在2023年1月1日—12月31日常用的35种静脉药物,通过Micromedex数据库及相关文献对静脉药物混合输注的相容性进行分析。结果根据文献查询及分析结果,制作了35种药物的相容性表。共计595种组合,其中相容279种(46.9%),不相容22种(3.7%),不确定28种(4.7%),未知的266种(44.7%)。结论ICU中混合输注现象普遍,但缺乏安全性证据和相关指南。迫切需要完善相容性数据,开发全面的静脉药物相容性资源,提供更安全的用药方案。Objective To evaluate the compatibility of commonly used intravenous drugs in the ICU of Hebei General Hospital and to propose optimization strategies.Methods Data from 35 intravenous drugs used in ICU from January 1 to December 31,2023 were analyzed using the Micromedex database and relevant literature.Results A compatibility chart for 35 drugs was created.Total 595 combinations,of which 279(46.9%)were compatible,22(3.7%)were incompatible,28(4.7%)were uncertain,and 266(44.7%)were unknown.Conclusion Drug co-administration is common in the ICU,but there is a lack of safety evidence and guidelines.There is an urgent to improve compatibility data and develop comprehensive resources to ensure safer intravenous drug administration.

关 键 词：重症监护室 静脉药物 混合输注 相容性 

分 类 号：R97[医药卫生—药品]