某院不孕症妇女生殖道沙眼衣原体、解脲脲原体感染及相关因素分析  

Analysis of genital tract chlamydia trachomatis and ureaplasma urealyticum infectionsand their associated factors in infertile women of a hospital

作　　者：郭玉 余慧汐 上官福亮 刘慧 苏银花[1] 李忠玉 GUO Yu;YU Huixi;SHANGGUAN Fuliang;LIU Hui;SU Yinhua;LI Zhongyu(School of Nursing University of South China,Hengyang,Hunan 421001,China)

机构地区：[1]南华大学护理学院,湖南衡阳421001

出　　处：《现代医药卫生》2025年第3期599-603,607,共6页Journal of Modern Medicine & Health

基　　金：国家自然科学基金项目(82272383);湖南省自然科学基金项目(2024JJ5349);湖南省研究生科研创新项目(CX20240088)。

摘　　要：目的 调查不孕症妇女生殖道沙眼衣原体(CT)和解脲脲原体(UU)感染的流行病学特点并探讨感染的相关因素。方法 回顾性分析2016年1月至2023年12月南华大学附属第一医院辅助生殖医学中心收治的1 113例不孕症妇女的临床资料,采用聚合酶链反应荧光探针法对阴道分泌物样本中的CT、UU进行核酸检测。结果 1 113例不孕症妇女生殖道CT、UU感染率分别为13.30%(148/1 113)和45.73%(509/1 113)。CT、UU感染率总体呈逐年上升趋势。25~<35岁、低收入、居住在农村、学历在初中及以下的不孕症妇女更易发生生殖道CT、UU感染,从事商业服务业者更易发生CT感染。同时,生殖道CT、UU感染互为危险因素。结论 不孕症妇女生殖道CT、UU感染率居高不下,应积极开展妇女生殖道CT、UU感染筛查工作,加强对易感人群及其性伴侣的健康宣教与临床干预。Objective To investigate the epidemiologic characteristics of genital tract chlamydia trachomatis(CT)and ureaplasma urealyticum(UU)infections in infertile women and to explore the factors associated with the infections.Methods The clinical data of 1113 infertile women admitted to the Center of Assisted Reproductive Medicine of the First Affiliated Hospital of the University of South China from January 2016 to December 2023 were retrospectively analyzed.PCR fluorescence probe was used to detect the nucleic acid of CT and UU in vaginal secretions.Results Among the 1113 infertile women investigated,the prevalence of CT and UU infections was 13.30%(148/1113)and 45.73%(509/1113),respectively.The infection rates of CT and UU were generally increasing year by year.Infertility women aged 25-<35 years old,low incomes,residing in rural areas,and with education levels of junior high school or below were more likely to develop reproductive tract CT and UU infections,and are more likely to have CT infection in commercial service workers.At the same time,CT and UU infection of reproductive tract are risk factors to each other.Conclusion The infection rate of CT and UU in reproductive tract of infertile women remains high.Screening of CT and UU infection in reproductive tract of women should be carried out actively,and health education and clinical intervention for susceptible population and their sexual partners should be strengthened.

关 键 词：沙眼衣原体 解脲脲原体 不孕症 妇女 

分 类 号：R711.6[医药卫生—妇产科学] R374[医药卫生—临床医学]