In-depth exploration of bioactive constituents,biosynthetic pathways,and pharmacological mechanisms of Angelica sinensis:implications for therapeutic development  

作　　者：Xiumin Zhang Lijun Fu Ruimei Zhang Li Liu Yongzheng Ma Na Zhang 

机构地区：[1]College of Food Engineering,Harbin University of Commerce,Harbin 150028,China [2]Beijing Academy of Food Sciences,Beijing 100068,China

出　　处：《Food Science and Human Wellness》2025年第2期404-420,共17页食品科学与人类健康(英文)

基　　金：funded by National Key R&D Program of China(2022YFF1100301,2023YFF1104403);Key R&D Project of Henan Province(231111112100)。

摘　　要：Angelica sinensis,a well-known traditional Chinese medicinal herb with the unique property of being both a medicine and an edible plant,has been widely used for promoting blood circulation,modulating immunity,and relieving pain.This review comprehensively investigates the extraction methods,structural characteristics,and biological activities of its primary bioactive components,such as polysaccharides,volatile oils,organic acids,and flavonoids.The biosynthesis pathways of these compounds,along with the key enzymes and transcription factors involved,are investigated to understand the factors influencing their synthesis and accumulation.Additionally,the biological activities of A.sinensis,including hepatoprotective,anti-inflammatory,immunemodulatory,anti-tumor,circulatory benefits,and neuroprotection,along with their underlying mechanisms are introduced.These findings provide a solid foundation for the development of A.sinensis as a valuable resource in functional foods and pharmaceutical products.

关 键 词：Angelica sinensis Bioactive compounds Biosynthesis pathways Biological activity Functional foods 

分 类 号：O62[理学—有机化学]