虫草在心血管疾病中的药理及临床研究进展  

Pharmacological and Clinical Research Progress of Cordyceps in Cardiovascular Diseases

作　　者：刘娅红 牛国栋 乔宇[1] 陈昱竹 LIU Yahong;NIU Guodong;QIAO Yu;CHEN Yuzhu(Department of Cardiac Arrhythmia,Kunming Medical University Affiliated Cardiovascular Hospital,Fuwai Yunnan Cardiovascular Hospital,Kunming 650000,Yunnan,China)

机构地区：[1]昆明医科大学附属心血管病医院云南省阜外心血管病医院心律失常一病区,云南昆明650000

出　　处：《中国分子心脏病学杂志》2024年第6期6521-6526,共6页Molecular Cardiology of China

基　　金：云南省阜外心血管病医院临床医学中心项目(2022YFKY016)

摘　　要：虫草内含丰富的生物活性成分,具有调节免疫、抗氧化应激和保护纤维化等作用,在肝脏、肾脏以及肺脏相关疾病中应用广泛,而在心血管疾病中的应用相对有限。已有研究通过动物实验和初步临床试验表明,虫草菌丝体可抑制心肌肥大和心肌损伤,改善心脏收缩功能,对于心脏具有保护作用。本文就目前虫草在心血管疾病中的药理机制和临床应用研究进行综述。Cordyceps is rich in bioactive components,which can regulate immunity,anti⁃oxidative stress and protect fibrosis.It is widely used in liver,kidney and lung diseases,but its application in cardiovascular diseases is relatively limited.Animal experiments and preliminary clinical trials have shown that Cordyceps mycelium can inhibit myocardial hypertrophy and myocardial injury,improve cardiac systolic function,and protect the hear.This article reviews the pharmacological mechanism and clinical application of Cordyceps in cardiovascular diseases.

关 键 词：虫草 心血管疾病 临床应用 药理作用 

分 类 号：R285.6[医药卫生—中药学]