Twelve‑month outcomes of single‑step transepithelial photorefractive keratectomy for moderate hyperopia and hyperopic astigmatism  

作　　者：Mahmoud Abdel‑Radi Mahmoud Rateb Mohamed G.A.Saleh Mohamed Omar M.Aly 

机构地区：[1]Department of Ophthalmology,Assiut University,Assiut University Hospital,6th Floor,71516 Assiut,Egypt

出　　处：《Eye and Vision》2025年第1期13-21,共9页眼视光学杂志(英文)

基　　金：Open access funding provided by The Science,Technology&Innovation Funding Authority(STDF)in cooperation with The Egyptian Knowledge Bank(EKB).

摘　　要：Background Conventional mechanical or alcohol-assisted photorefractive keratectomy(PRK)techniques for cor‑rection of hyperopia and hyperopic astigmatism were associated with inconsistent results.The aim of this study is to evaluate the 12-month visual and refractive outcomes of the relatively new single-step transepithelial photorefractive keratectomy(TE-PRK)for moderate hyperopia and hyperopic astigmatism.Methods This is a prospective interventional study.Forty-eight eyes of 30 patients with moderate hyperopia or hyperopic astigmatism with a cycloplegic spherical equivalent refraction(SEQ)between 2.0 and 4.5 diopters(D)underwent single-step StreamLight®TE-PRK using EX500 excimer laser(Alcon Laboratories,USA).The main outcome measures were recorded at 6 and 12 months postoperatively including assessment of logarithm of the minimum angle resolution(logMAR)uncorrected and corrected distance visual acuity(UDVA,CDVA),cycloplegic refraction,corneal topographic changes as well as post-PRK peripheral haze grading.Results The mean preoperative cycloplegic SEQ was signifcantly reduced from 3.21±0.61 D to 0.35±0.04 D and 0.41±0.04 D at 6 and 12 months,respectively(P<0.001).The mean preoperative UDVA signifcantly improved from 0.53±0.02 logMAR to 0.07±0.01 logMAR and 0.08±0.01 logMAR at 6 and 12 months,respectively(P<0.001)while the mean preoperative logMAR CDVA showed non-signifcant change over time throughout the study(P=0.135).At the end of the study,41 eyes(85.4%)achieved UDVA of 20/25 or better and no eye lost any lines of CDVA.Thirty-eight eyes(79.1%)had a postoperative cycloplegic cylinder of 0.5 D or less at 12 months.The mean preoperative mean keratometry showed signifcant increase at 6 and 12 months postoperatively(P<0.001)while there was no signifcant change between the two postoperative visits denoting topographic stability(P=0.058).The mean postoperative Q value at 6 and 12 months showed a signifcant prolate shift(P<0.001).No haze was observed in 62.5%and 85.4%of the enrolled eyes at 6 and 12 months,re

关 键 词：Single-step PRK StreamLight PRK HYPEROPIA Hyperopic astigmatism Hyperopic PRK 

分 类 号：R73[医药卫生—肿瘤]