基于技术专利视角的合成生物学脱氧核糖核酸(DNA)计算发展态势研究  

Development Trend Analysis of Synthetic Biology-DNA Computing from the Perspective of Technical Patents

作　　者：马丽丽 相强宇 高婉莹 吴宗震 左锟澜 赵晏强[1] 焦洪涛[3] 刘欢 Ma Lili;Xiang Qiangyu;Gao Wanying;Wu Zongzhen;Zuo Kunlan;Zhao Yanqiang;Jiao Hongtao;Liu Huan(National Science Library(Wuhan),Chinese Academy of Sciences,Wuhan 430071,China;School of humanities and social sciences,University of Science and Technology of China,Hefei 230026,China;Law school,Huazhong University of Science and Technology,Wuhan 430074,China;Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China)

机构地区：[1]中国科学院武汉文献情报中心,湖北武汉430071 [2]中国科学技术大学人文与社会科学学院,安徽合肥230026 [3]华中科技大学法学院,湖北武汉430074 [4]中国科学院武汉病毒研究所,湖北武汉430071

出　　处：《科技管理研究》2025年第2期134-141,共8页Science and Technology Management Research

基　　金：国家重点研发计划“合成生物学”重点专项项目“合成生物学伦理、政策法规框架研究”(2018YFA0902400);中国科学院项目“中国科学院高质量数据池和数据产品服务体系建设”(2019WQZX012);国家知识产权局专利分析项目“合成生物学关键核心技术专利分析研究”(FX202309)。

摘　　要：DNA计算作为合成生物学领域的研究重点,具有潜在的应用价值。鉴于当前人工智能和合成生物学交叉融合并快速发展,分析研判当前DNA计算领域的技术发展态势,有利于我国在相关领域的技术布局和战略规划。基于专利情报分析视角,对全球范围内1982—2023年的合成生物学DNA计算相关专利数据进行检索,从专利申请趋势、技术构成、技术来源国、目标市场、主要申请人、技术集中度等多维度对合成生物学DNA计算技术领域进行发展态势分析。结果发现,进入21世纪以来,DNA计算领域相关技术专利申请增长迅速,中美两国是该领域专利布局的两大领先国家,关键分支领域包括DNA纳米技术、DNA回路和DNA计算相关技术的应用等三方面,相较于美国,中国要加强布局DNA计算在生物治疗、信息处理等领域的技术研发,推动产学研合作和技术的知识产权保护。DNA computing,as a research focus in the field of synthetic biology,has potential application values.Given the current cross fusion and rapid development of artificial intelligence and synthetic biology,analyzing and assessing the current development trend in the field of DNA computing is beneficial for China's technological layout and strategic planning.Based on the perspective of patent intelligence analysis,this paper analyzes the synthetic biology DNA computing related patents data during 1982-2023 worldwide from multiple dimensions including patent application trends,technology composition,technology source countries,target markets,main applicants,and technology concentration.The results show that since the beginning of the 21st century,patent applications in DNA computing related field have grown rapidly,with China and United States being the two leading countries,the key branch areas include DNA nanotechnology,DNA circuits,and the application of DNA computing related technologies.Compared with the United States,our country need to strengthen the layout of DNA computing technology research and development in biological therapy,information processing,and other fields,promoting industry-university-research cooperation,and strengthen the intellectual property rights protection.

关 键 词：合成生物学 DNA计算 专利分析 多维可视化 

分 类 号：G306[文化科学] G350