A型肉毒毒素联合医用皮肤表面减张器治疗腹部瘢痕疙瘩的临床研究  

Clinical experience of treating abdominal keloid with botox type A combined with medical skin surface tensioner

作　　者：郭琳琳 丁岩[1] 郭洁[1] 白晓林 GUO Lin-lin;DING Yan;GUO Jie;BAI Xiao-lin(Department of Plastic and Aesthetic Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院整形美容外科,郑州450000

出　　处：《医药论坛杂志》2025年第2期194-197,202,共5页Journal of Medical Forum

摘　　要：目的 探究在腹部瘢痕疙瘩的临床治疗中,将A型肉毒毒素与医用皮肤表面减张器二者共同使用时的效果。方法 选取2021年3月至2022年3月郑州大学第一附属医院整形美容外科收治的腹部瘢痕疙瘩患者106例,采用随机数字表法将患者分为对照组和研究组各53例,两组均给予局部X线照射治疗,对照组采用医用皮肤表面减张器减张,研究组则于对照组基础上注射A型肉毒毒素,以瘢痕宽度、温哥华瘢痕评分量表(vancouver scar rating scale,VSS)评分以及疗效满意度作为观察指标,进行组间治疗效果对比。结果 术前,组间瘢痕宽度比较差异无统计学意义(P>0.05),但术后6个月,研究组瘢痕宽度与对照组相比明显更低,差异有统计学意义(P<0.05);术前组间VSS评分差异无统计学意义(P>0.05),但术后6个月,研究组评分与对照组相比明显更低,差异有统计学意义(P<0.05);术后,研究组疗效满意度与对照组比较明显更高,差异有统计学意义(P<0.05)。结论 在临床中对腹部瘢痕疙瘩患者进行治疗时,将A型肉毒毒素配合医用皮肤表面减张器使用,对于改善瘢痕疙瘩外观,缩小瘢痕具有效果,且患者对其有较高的满意度,值得推广。Objective To evaluate the clinical experience of botulinum toxin type A combined with medical skin surface tensioner in the treatment of abdominal keloid.Methods The selection of case samples started from March 2021 and ended in March 2022.A total of 106 abdominal keloid patients from the Plastic and Aesthetic Surgery Department of the First Affiliated Hospital of Zhengzhou University were included,and randomly divided into control group and study group,with 53 cases in each group using the random number table method.Both groups were treated with local X-ray irradiation.The control group was only treated with medical skin surface tensioner,while the study group was simultaneously injected with botox type A on the basis of the control group.Scar width,vancouver scar rating scale(VSS) score and efficacy satisfaction were used as observation indexes to compare the treatment effect between groups.Results There were no significant differences in scar width and VSS score between the two groups before surgery(P>0.05).At 6 months after operation,scar width in the study group was lower than that in the control group(P<0.05),and VSS score in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The patients in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion For patients with abdominal keloid,the combination of medical skin surface tensioner and botulinum toxin injection type A after surgery is effective,which can effectively improve the appearance of keloid and reduce the width of scar,and the patient satisfaction is high,which is worthy of promotion.

关 键 词：A型肉毒毒素 医用 皮肤表面减张器 腹部 瘢痕疙瘩 

分 类 号：R622[医药卫生—整形外科]