临床血液传染病检测及流行病学调查分析  

Investigation and analysis of clinical blood infectious disease detection and epidemiology

作　　者：冯巧枝 FENG Qiao-zhi(Clinical Laboratory,Henan Chest Hospital,Zhengzhou 450003,China)

机构地区：[1]河南省胸科医院检验科,郑州450003

出　　处：《医药论坛杂志》2025年第1期70-74,共5页Journal of Medical Forum

摘　　要：目的通过对本院患者四项传染病检测结果进行分析,为防控工作提供参考依据。方法随机调查河南省胸科医院2019—2023年住院患者35097名,抽取的抗凝静脉血,采用磁微粒化学发光法进行乙肝、丙肝、艾滋以及梅毒四项传染病进行检测,检测实验数据用SPSS21.0软件进行统计分析。结果35097名患者,HBsAg、抗-HCV以及抗-TP阳性率分别为4.29%(1507/35097)、1.30%(455/35097)、1.26%(441/35097),抗-HIV经WB确认阳性率为0.01%(4/35097)。男性HBsAg阳性率、抗-HCV阳性率、抗-TP阳性率均高于女性,差异有统计学意义(P<0.05)。32岁以上人群的HBsAg阳性率、抗-HCV阳性率、抗-TP阳性率均高于31岁以下,差异有统计学意义(P<0.05)。抗-HBs、抗-HBc、HBeAg以及抗-HBe阳性率分别为46.94%(16474/35097)、42.68%(14979/35097)、0.64%(224/35097)和3.40%(1193/35097)。乙肝两对半出现18种模式,其中乙肝两对半全阴性率为31.87%(11186/35097),大三阳(135)和小三阳(145)阳性率分别为0.53%(185/35097)和3.18%(1116/35097)。结论本院住院患者四项传染病均不同程度的阳性率,其中乙肝阳性率最高。乙肝、丙肝、梅毒发病率在不同年龄、不同性别均有差异,男性、32岁以上人群发病率较高。本地疫苗防控效果显著。同时,临床还需严格预防职业暴露,控制院内感染,对医患人员及医院都有非常重要的意义。Objective By analyzing the test results of four infectious diseases in our hospital,it provides reference for the prevention and control work.Methods A random survey of 35097 hospitalized patients from 2019 to 2023 of anticoagulant venous blood,including hepatitis B,hepatitis C,AIDS and syphilis by magnetic particles,were detected.The experimental data were statistically analyzed by SPSS 21.0 software.Results In 35097 patients,HBsAg,anti-HCV and anti-TP were 4.29%(1507/35097),1.30%(455/35097),and 1.26%(441/35097),respectively,and anti-HIV was 0.01%(4/35097).HBsAg,anti-HCV,and anti-TP were higher in men than women,and the difference was significant(P<0.05).HBsAg,anti-HCV and anti-TP in people aged over 32 years were higher than 31 years,with a statistically significant difference(P<0.05).Anti-HBs,anti-HBc,HBeAg and anti-HBe positive rates were 46.94%(16474/35097),42.68%(14979/35097),0.64%(224/35097)and 3.40%(1193/35097),respectively.There were 18 modes,among which the full negative rate of hepatitis B was 31.87%(11186/35097),and the positive rate of San San Yang(135)and Xiao Sanyang(145)were 0.53%(185/35097)and 3.18%(1116/35097),respectively.Conclusion The positive rate of four infectious diseases in our hospital was different degrees,among which the positive rate of hepatitis B was the highest.The incidence of hepatitis B,hepatitis C and syphilis varies among different ages and sexes,and the incidence is higher in men and people over 32 years old.The prevention and control effect of local vaccines is remarkable.At the same time,clinical treatment also needs to strictly prevent occupational exposure,and control nosocomial infection,which is of great significance to both doctors and patients and the hospital.

关 键 词：HBsAg 抗-HCV 抗-HIV 抗-TP 抗-HBS HBeAg 抗-HBE 抗-HBC 

分 类 号：R446.1[医药卫生—诊断学]