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作 者:石世林 许严锴 吕福强 刘克坚[2] SHI Shilin;XU Yankai;LV Fuqiang;LIU Kejian(School of Medicine,Shihezi University,Shihezi,Xinjiang 832000;Department of Cardiology,First Affiliated Hospital of Shihezi University,Shihezi,Xinjiang 832000)
机构地区:[1]石河子大学医学院,新疆石河子市832000 [2]石河子大学第一附属医院心内科,新疆石河子市832000
出 处:《兵团医学》2024年第3期16-20,共5页Journal of BingTuan Medicine
基 金:兵团科技计划项目:重点领域科技攻关计划(S2022AB2002)
摘 要:目的 运用统计学方法分析兵团南疆地区老年非瓣膜性心房颤动(Non-valvular Atrial Fibrillation,NVAF)住院患者各项影响因素,为制定具有地区特征的防治措施提供依据。方法 收集2014年1月~2023年10月在第二师焉耆人民医院、第三师人民医院(喀什分院)住院的935例老年患者,依据是否诊断为NVAF分为NVAF组(n=466)及对照组(n=469),分析比较两组间临床指标差异。结果 NVAF组高血压、心力衰竭、入院心率、N%、RDW-CV、AST、ALT、TBiL、DBiL、IBiL、BUN、Cr、UA、Glu、hsCRP、Hcy、CysC、D-Dimer、LAD、LVDs、LVDd高于对照组,SBP、PLT、RDW、LY、Hb、Ca^(2+)、TG、TC、HDL-C、LDL-C、EF低于对照组,差异有统计学意义(P<0.05)。校正多因素Logistic回归显示入院心率(OR=1.023,95%CI:1.11-1.036,P<0.001)、心力衰竭(OR=12.793,95%CI:3.464-47.240,P<0.001)和LAD(OR=1.213,95%CI:1.169-1.258,P<0.001)是老年NVAF住院患者危险因素;EF(OR=0.926,95%CI:0.895-0.958,P<0.001)和LDL-C(OR=0.631,95%CI:0.493-0.806,P<0.001)是老年NVAF住院患者保护因素。结论 老年NVAF住院患者的入院心率较快、LDL-C较低、LAD较宽、EF较低,且老年NVAF住院患者更易合并心力衰竭,本研究为预防和延缓NVAF发生和发展提供了依据。Objective Using statistical methods to analyze various influencing factors of elderly hospitalized patients with nonvalvular atrial fibrillation(NVAF)in the southern region of the XPCC,providing a basis for developing prevention and treatment measures with regional characteristics.Methods Collect 935 elderly patients admitted to Yanqi People's Hospital of the Second Division and Kashgar Branch of the Third Division from January 2014 to October 2023,and divide them into the NVAF group(n=466)and the control group(n=469)based on whether they have been diagnosed with NVAF.Analyze and compare the clinical indicators between the two groups.Results The NVAF group had higher levels of hypertension,heart failure,admission heart rate,N%,RDW-CV,AST,ALT,TBiL,DBiL,IBiL,BUN,Cr,UA,Glu,hsCRP,Hcy,CysC,D-Dimer,LAD,LVDs,and LVDd than the control group,while SBP,PLT,RDW,LY,Hb,Ca^(2+),TG,TC,HDL-C,LDL-C,and EF were lower than the control group,with statistical significance(P<0.05).Adjusted multiple logistic regression showed that admission heart rate(OR=1.023,95%CI:1.11-1.036,P<0.001),heart failure(OR=12.793,95%CI:3.464-47.240,P<0.001),and LAD(OR=1.213,95%CI:1.169-1.258,P<0.001)were risk factors for elderly hospitalized patients with NVAF;EF(OR=0.926,95%CI:0.895-0.958,P<0.001)and LDL-C(OR=0.631,95%CI:0.493-0.806,P<0.001)are protective factors for elderly hospitalized patients with NVAF.Conclusions Elderly hospitalized patients with NVAF have faster admission heart rate,lower LDL-C,wider LAD,lower EF,and are more prone to heart failure.This provides a basis for preventing and delaying the occurrence and development of NVAF.
分 类 号:R541.75[医药卫生—心血管疾病]
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