小剂量胺碘酮维持治疗小儿心律失常的临床效果与安全性分析  

Clinical Efficacy and Safety Analysis of Low-dose Amiodarone Maintenance Therapy for Pediatric Arrhythmia

作　　者：俞玲灵 Yu Lingling(Shaoxing Central Hospital Qianqing Branch,Shaoxing,Zhejiang 312000)

机构地区：[1]绍兴市中心医院医共体钱清分院,浙江绍兴312000

出　　处：《中外健康》2024年第3期49-51,共3页

摘　　要：分析小儿心律失常患儿应用小剂量胺碘酮维持治疗的临床效果与安全性。选择2022年5月―2023年3月期间绍兴市中心医院医共体钱清分院收治的90例小儿心律失常患儿,采用随机数字表法分为参照组和观察组,每组各45例,参照组给予盐酸普罗帕酮片治疗,观察组给予小剂量胺碘酮维持治疗。对比两组患者的心功能、治疗效果、不良反应发生率。结果显示,观察组患儿治疗有效率显著高于参照组(P<0.05);治疗后,观察组患儿心功能相关指标均显著优于参照组(P<0.05);观察组患儿不良反应发生率显著低于参照组(P<0.05)。研究发现,对于小儿心律失常患儿,使用小剂量的胺碘酮维持疗法不仅能提高临床疗效,还能降低患儿的不良反应发生率,值得推广应用。To analyze the clinical efficacy and safety of low-dose amiodarone maintenance therapy in children with arrhythmia.Ninety children with arrhythmia admitted to Shaoxing Central Hospital Qianqing Branch from May 2022 to March 2023 were selected and divided into a reference group and an observation group by the random number table method,with 45 cases in each group.The reference group was treated with propafenone hydrochloride tablets,and the observation group was treated with low-dose amiodarone maintenance therapy.The cardiac function,treatment effect and adverse reactions of the two groups were compared.The results showed that the treatment effective rate of the children in the observation group was significantly higher than that in the reference group(P<0.05).After treatment,the cardiac function related indexes of the children in the observation group were significantly better than those in the reference group(P<0.05),and the incidence of adverse reactions of the children in the observation group was significantly lower than that in the reference group(P<0.05).The study found that for children with arrhythmia,the use of low-dose amiodarone maintenance therapy can not only improve the clinical efficacy,but also reduce the incidence of adverse reactions in children,which is worthy of promotion and application.

关 键 词：小儿心律失常 胺碘酮 治疗效果 

分 类 号：R725.4[医药卫生—儿科]