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作 者:乔逸[1] 张寅生[1] 周敬敏[1] 刘广华[1] 肖河[1] QIAO Yi;ZHANG Yinsheng;ZHOU Jingmin;LIU Guanghua;XIAO He(Department of Urology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing,100730,China)
机构地区:[1]中国医学科学院北京协和医院泌尿外科,北京100730
出 处:《临床泌尿外科杂志》2025年第2期124-127,共4页Journal of Clinical Urology
基 金:中央高水平医院临床科研业务费(No:2022-PUMCH-C-034)。
摘 要:目的:探讨泌尿系结石患者术前尿亚硝酸盐阳性率及其相关危险因素,为围手术期管理提供依据。方法:回顾性分析2023年10月1日—2024年10月1日在北京协和医院接受泌尿系结石碎石手术的280例患者。收集患者的基本信息、术前尿亚硝酸盐检测结果、结石特征及相关临床资料,采用单因素分析和多元logistic回归分析术前尿亚硝酸盐阳性的危险因素。结果:术前尿亚硝酸盐阳性率为6.79%。单因素分析显示,性别、结石最大径、结石成分等因素与尿亚硝酸盐阳性显著相关。多元logistic回归分析发现,女性、结石最大径>2 cm和结石含有碳酸磷灰石成分是尿亚硝酸盐阳性的独立危险因素(P<0.05)。结论:女性、结石最大径>2 cm以及结石含有碳酸磷灰石成分显著增加术前尿亚硝酸盐阳性风险。应在术前识别高危患者,采取针对性措施以降低围手术期感染风险。Objective:To investigate the preoperative urinary nitrite positivity rate and its associated risk factors in patients with urolithiasis,providing guidance for perioperative management.Methods:A retrospective analysis was conducted on 280 patients who underwent urinary stone fragmentation surgery at Peking Union Medical College Hospital from October 1^(st),2023,to October 1^(st),2024.Basic patient information,preoperative urinary nitrite test results,stone characteristics,and related clinical data were collected.Univariate analysis and multivariate logistic regression were used to identify risk factors in preoperative urinary nitrite positivity.Results:The preoperative urinary nitrite positivity rate was 6.79%.Univariate analysis showed significant associations between urinary nitrite positivity and factors such as gender,stone size,and stone composition.Multivariate logistic regression identified female gender,stone size>2 cm,and the presence of carbonate apatite in the stones as independent risk factors in urinary nitrite positivity(P<0.05).Conclusion:Female gender,stone size>2 cm,and the presence of carbonate apatite in the stones significantly increase the risk of preoperative urinary nitrite positivity.High-risk patients should be identified preoperatively to implement targeted measures to reduce perioperative infection risk.
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