体外受精治疗前服用滇女金丸对卵巢低反应肾虚证患者卵巢功能及治疗结局的影响  

Impact of Ovarian Function and Treatment Outcome in Patients with Ovarian Insufficiency and Kidney Deficiency Syndrome Who Took Dianvjin Pills before In Vitro Fertilization Treatment.

作　　者：许娇 樊雪娇 任海琴[1] Xu Jiao;Fan Xuejiao;Ren Haiqin(Shenyang Jinhua Hospital,Shenyang,110000,China)

机构地区：[1]沈阳菁华医院,辽宁沈阳110000

出　　处：《成都中医药大学学报》2025年第2期52-56,共5页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年项目(81503272)。

摘　　要：目的:分析在体外受精(in vitro fertilization,IVF)周期治疗前服用滇女金丸4周患者的疗效,以评估应用滇女金丸对卵巢低反应(POR)患者(肾虚证)卵巢功能及IVF治疗的影响。方法:通过医院管理信息系统(HIS系统),在沈阳菁华医院2021年6月-2023年3月行IVF治疗的病例中,筛选出IVF周期治疗前服用滇女金丸4周的POR患者(肾虚证)62例为治疗组,并筛选一般情况及卵巢功能基本相当的未进行任何干预、直接进入IVF周期治疗的POR患者(肾虚证)57例为对照;比较两组取卵数和优质胚胎数,并对治疗组服药前后基础激素水平进行比较。结果:与治疗前比较,治疗组服药后卵泡刺激素(FSH)水平降低(P<0.05)、雌激素(E2)水平升高(P<0.05),提示治疗组对卵巢功能有改善作用;与对照组比较,治疗组在IVF治疗中,获卵数和可用胚胎数增多(P<0.05)。结论:在进入IVF周期治疗前,服用滇女金丸,能改善POR患者(肾虚证)的卵巢功能、提高获卵数及可用胚胎数,提高IVF疗效。Objective:Analyzing the efficacy of taking Dianvjin Pills for 4 weeks before in vitro fertilization(IVF)cycles to evaluate the impact of using Dianujin Pills on ovarian function and IVF treatment in patients with poor ovarian response(POR)(with Kidney deficiency).Methods:Using the Hospital Information System(HIS)at Shenyang Jinhua Hospital,62 cases of POR patients(with Kidney deficiency)who took Dianvjin Pills for 4 weeks before undergoing IVF treatment from June 2021 to March 2023 were selected as the treatment group.They were compared with 57 POR patients(with Kidney deficiency)in the control group who received no prior interventions and directly proceeded to IVF treatment,matched for general conditions and basic ovarian function.The comparison involved assessing the number of retrieved eggs and high-quality embryos between the two groups,as well as comparing the baseline hormone levels before and after medication in the treatment group.Results:In comparison with before treatment,the medication group showed a decrease in follicle-stimulating hormone(FSH)levels(P<0.05)and an increase in estrogen(E 2)levels(P<0.05),indicating an improvement in ovarian function in the treatment group.In comparison with the control group,the treatment group had an increase in the number of retrieved eggs and available embryos during IVF treatment(P<0.05).Conclusion:Before starting IVF treatment,taking Dianvjin Pills can improve ovarian function in POR patients(with Kidney deficiency),increase the number of retrieved eggs and available embryos,and enhance the effectiveness of IVF.

关 键 词：卵巢低反应 肾虚证 体外受精 卵泡刺激素 雌激素 获卵数 可用胚胎数 

分 类 号：R256.5[医药卫生—中医内科学] R717[医药卫生—中医学]