中医辨证“饮食-运动-心理”模式对单纯性肥胖儿童的糖脂代谢及炎症的影响  

Effects of Diet-Exercise-Psychological Model on Glucose and Lipid Metabolism and Inflammation in Children with Simple Obesity

作　　者：焦晓楠 白青云[1] 林琳 刘芳[1] 李亚[1] 梁上艳 JIAO Xiaonan;BAI Qingyun;LIN Lin;LIU Fang;LI Ya;LIANG Shangyan(Department of Pediatrics,The First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Henan 450000,China)

机构地区：[1]河南中医药大学第一附属医院儿科,郑州450000

出　　处：《西南医科大学学报》2025年第2期221-225,共5页Journal of Southwest Medical University

基　　金：河南省中医药科学研究专项课题(2024ZY3016)。

摘　　要：目的观察中医辨证“饮食-运动-心理”模式在单纯性肥胖儿童中的应用效果,及其对糖脂代谢及炎症反应的影响。方法回顾性分析2022年7月至2023年12月我院收治的68例单纯性肥胖儿童临床资料,根据其接受的不同护理干预模式分组,通过直接匹配法1∶1匹配后,分成对照组(实施常规干预,n=34)和观察组(实施中医辨证“饮食-运动-心理”模式,n=34)。采用spss软件分析数据,比较肥胖指标[体脂率、体质量指数(BMI)],糖脂代谢[低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、总胆固醇(TC)、甘油三酯(TG)、空腹血糖(FPG)、胰岛素抵抗指数(HOMA-IR)],炎症指标[肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、IL-6],身体素质(立定跳远、仰卧起坐、坐位体前屈、握力及肺活量)。结果两组儿童干预前减肥指标、糖脂代谢指标及炎性指标比较,差异无统计学意义(P>0.05)。两组儿童干预后减肥指标体脂率、BMI和糖脂代谢指标LDL-C、TC、TG、FPG、HOMA-IR及炎性指标TNF-α、IL-1β、IL-6均低于干预前(P<0.05),干预后脂代谢指标HDL-C及身体素质指标立定跳远、仰卧起坐、坐位体前屈、握力、肺活量均高于干预前(P<0.05)。干预后观察组儿童减肥指标体脂率、BMI和糖脂代谢指标LDL-C、TC、TG、FPG、HOMA-IR及炎性指标TNF-α、IL-1β、IL-6均低于对照组儿童(P<0.05),干预后观察组儿童脂代谢指标HDL-C及身体素质指标立定跳远、仰卧起坐、坐位体前屈、握力、肺活量均高于对照组儿童(P<0.05)。结论中医辨证“饮食-运动-心理”模式可降低单纯性肥胖儿童的体脂率及BMI,改善其糖脂代谢及炎症反应,提升身体素质。Objective To observe the effect of“diet-exercise-psychological”mode in TCM syndrome differentiation in children with simple obesity,and its influence on glucose and lipid metabolism and inflammation.Methods Clinical data of 68 children with simple obesity admitted to our hospital from July 2022 to December 2023 were retrospectively analyzed.According to the different nurs⁃ing intervention modes received by children with simple obesity,they were divided into the control group(routine intervention,n=34)and the observation group(diets-exercise-psychological mode of TCM syndrome differentiation)after 1∶1 matching by direct matching method(n=34).Spss software was used to analyze the data.The indexes of obesity(body fat percentage,BMI),glucose and lipid metabolism(LDL-C,HDL-C,TC,TG,FPG,HOMA-IR),inflammation(TNF-α,IL-1β,IL-6),physical fitness(standing long jump,sit-up,seated forward bend,grip strength and vital capacity)were compared.Results There were no differ⁃ences in weight loss index,glucose and lipid metabolism index,and inflammatory index between the two groups of children with simple obesity before intervention(P>0.05).After the intervention,the weight loss indicators such as body fat percentage,BMI,and glyco⁃lipid metabolism indicators LDL-C,TC,TG,FPG,HOMA-IR,as well as inflammatory indicators TNF-α,IL-1β,IL-6 in both groups of children were all lower than before the intervention(P<0.05).Post-intervention,lipid metabolism indicators HDL-C and physical fitness indicators including standing long jump,sit-ups,sit-and-reach,hand grip strength,and vital capacity were all higher than before the intervention(P<0.05).After the intervention,the weight loss indicators such as body fat percentage and BMI,as well as glycolipid metabolism indicators LDL-C,TC,TG,FPG,HOMA-IR,and inflammatory indicators TNF-α,IL-1β,IL-6 in the observation group children were all lower than those in the control group children(P<0.05).Post-intervention,lipid metabolism indi⁃cator HDL-C and physical fitness indicators includin

关 键 词：单纯性肥胖 中医辨证 疗效 糖脂代谢 体质量指数 

分 类 号：R272[医药卫生—中医儿科学]