Establishing and popularizing a standard pathological diagnostic model of endoscopic submucosal dissection specimens in China  

作　　者：Chun Xu Ling Chen An-Ning Feng Ling Nie Yao Fu Lin Li Wei Li Qi Sun 

机构地区：[1]Department of Pathology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,Jiangsu Province,China

出　　处：《World Journal of Gastrointestinal Endoscopy》2025年第3期60-67,共8页世界胃肠内镜杂志(英文)

基　　金：Supported by the Medical Education Research Project from Nanjing Drum Tower Hospital,No.2021-7;the Clinical Trials Fund from Nanjing Drum Tower Hospital,No.2022-YXZX-XH-04;National Natural Science Foundation of China,No.82203063.

摘　　要：BACKGROUND Endoscopic submucosal dissection(ESD)is a standardized therapeutic approach for early carcinoma of the digestive tracts.In this regard,the process of histopathological diagnosis requires standardization.However,the uneven development of healthcare in China,especially in eastern and western China,creates challenges for sharing a standardized diagnostic process.AIM To optimize the process of ESD specimen sampling,embedding and slide production,and to provide complete and accurate pathological reports.METHODS We established a practical process of specimen sampling,created standardized reporting templates,and trained pathologists from neighboring hospitals and those in the western region.A training effectiveness survey was conducted,and the collected data were assessed by the corresponding percentages.RESULTS A total of 111 valid feedback forms have been received,among which 58%of the participants obtained photographs during specimen collection,whereas the percentage increased to 79%after training.Only 58%and 62%of the respondents ensured the mucosal tissue strips were flat and their order remained unchanged;after training,these two proportions increased to 95%and 92%,respectively.Approximately half the participants measured the depth of the submucosal infiltration,which significantly increased to 95%after training.The percentage of pathologists who did not evaluate lymphovascular invasion effectively reduced.Only 22%of the participants had fixed clinic-pathological meetings before training,which increased to 49%after training.The number of participants who had a thorough understanding of endoscopic diagnosis also significantly increased.CONCLUSION There have been significant improvements in the process of specimen collection,section quality,and pathology reporting in trained hospitals.Therefore,our study provides valuable insights for others facing similar challenges.

关 键 词：Endoscopic submucosal dissection specimen Specimen processing Pathological diagnosis Gastrointestinal endoscopy Continuing education 

分 类 号：R73[医药卫生—肿瘤]