Modified single-port laparoscopic appendectomy using needle-type grasping forceps vs conventional three-port laparoscopic appendectomy for acute uncomplicated appendicitis  

作　　者：Yang Chen Shi-Gang Guo Xin-Ao Fu Zong-Qi Fan Jie-Qing Yuan Xiao-Xin Zhang Huan Liu Zhu Liu Yong-Shuai Huang Lei Song 

机构地区：[1]Department of Gastrointestinal Surgery,Chaoyang Central Hospital,China Medical University,Chaoyang 122000,Liaoning Province,China [2]Department of Gastrointestinal Surgery,Chaoyang Central Hospital,Postgraduate Training Base of China Medical University and Jinzhou Medical University,Chaoyang 122000,Liaoning Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2025年第4期324-332,共9页世界胃肠外科杂志(英文)

基　　金：Supported by the Natural Science Foundation of Liaoning Province,No.2023-MS-354;the Science and Technology Project for Youth of Chaoyang Central Hospital,China Medical University,Liaoning Province,China.

摘　　要：BACKGROUND Single-port laparoscopic appendectomy is an advanced minimally invasive surgery that involves the use of upgraded instruments and equipment.We previously modified single-port laparoscopic appendectomy with needle-type grasping forceps(mSLAN)for patients with simple appendicitis,but the feasibility and safety of our modified procedure need further evaluation in a highquality clinical study.AIM To compare the short-term clinical outcomes of mSLAN with those of conventional three-port laparoscopic appendectomy(CLA)for patients with acute uncomplicated appendicitis.METHODS This single-center,single-blind,prospective,randomized controlled trial included patients who underwent emergency laparoscopic appendectomy for acute uncomplicated appendicitis at our center between April 2024 and August 2024.Patients were randomly divided into the mSLAN group or the CLA group via computergenerated randomization.The primary endpoint was the 24-hour postoperative visual analog scale(VAS)score,and the secondary endpoints included the operative time,24-hour postoperative inflammatory response biomarkers(including white blood cells,the neutrophil ratio,interleukin-6,and C-reactive protein),time to first postoperative exhaust,time to first out-of-bed activity,postoperative length of hospital stay,cost of hospitalization,and incidence of postoperative complications.RESULTS A total of 72 patients were enrolled and randomly divided into 2 groups:The mSLAN group(n=36)and the CLA group(n=36).The 24-hour VAS scores,24-hour postoperative inflammatory response marker levels,first postoperative exhaust times,first out-of-bed activity times,postoperative lengths of hospital stay,operative times,or hospitalization costs did not significantly differ between the two groups.No postoperative complications,including incision infection or hernia,abdominal abscess or intestinal obstruction,were observed during the 1-month postoperative follow-up in either group.CONCLUSION Compared with the CLA protocol,the mSLAN protocol for acute uncomplicate

关 键 词：Single-port laparoscopy Minimally invasive surgery Acute appendicitis APPENDECTOMY Randomized controlled trial 

分 类 号：R65[医药卫生—外科学]