酶联免疫吸附法检测与快速血浆反应素试验在梅毒检验中的价值分析  

Analysis of the Value of Enzyme-linked Immunosorbent Assay and Rapid Plasma Reagin Test in Syphilis Test

作　　者：唐衍兴 谢明明 TANG Yanxing;XIE Mingming(Department of Laboratory,Nanchang Xinjian District Center for Disease Control and Prevention,Nanchang 330100,Jiangxi,China;Department of Laboratory,Nanchang Economic and Technological Development Zone People's Hospital/Nanchang Integrated Traditional Chinese and Western Medicine Hospital Economic and TechnologicalDevelopment Zone Branch,Nanchang 330032,Jiangxi,China)

机构地区：[1]南昌市新建区疾病预防控制中心检验科,江西南昌330100 [2]南昌市经济技术开发区人民医院/南昌市中西医结合医院经开分院检验科,江西南昌330032

出　　处：《医学信息》2025年第6期143-146,共4页Journal of Medical Information

摘　　要：目的分析酶联免疫吸附法检测(ELISA)与快速血浆反应素试验(RPR)在梅毒检验中的应用价值。方法以2023年1月-2024年1月南昌市新建区疾病预防控制中心接诊的85例疑似梅毒患者为研究对象,依次行ELISA与RPR检测,统计两种检测方式的阳性检出率,比较ELISA与RPR在不同分期梅毒患者中的阳性检出率,分析二者在梅毒检验中的诊断效能。结果ELISA的梅毒阳性检出率高于RPR(P<0.05)。ELISA对一期、二期梅毒患者的阳性检出率高于RPR(P<0.05),但ELISA与RPR对三期梅毒患者的阳性检出率比较,差异无统计学意义(P>0.05)。ELISA在梅毒检验中的诊断准确性、敏感度、特异度高于RPR(P<0.05)。结论ELISA与RPR在梅毒检验中均具有一定价值,其中ELISA的诊断效能相对更高。Objective To analyze the application value of enzyme-linked immunosorbent assay(ELISA)and rapid plasma reagin test(RPR)in syphilis test.Methods From January 2023 to January 2024,85 patients with suspected syphilis admitted to Nanchang Xinjian District Center for Disease Control and Prevention were selected as the research objects.ELISA and RPR were performed in turn.The positive detection rates of the two detection methods were counted.The positive detection rates of ELISA and RPR in patients with different stages of syphilis were compared,and the diagnostic efficacy of the two methods in syphilis test was analyzed.Results The positive rate of syphilis in ELISA was higher than that in RPR(P<0.05).The positive detection rate of ELISA in patients with primary and secondary syphilis was higher than that of RPR(P<0.05),but there was no significant difference in the positive detection rate of ELISA and RPR in patients with tertiary syphilis(P>0.05).The diagnostic accuracy,sensitivity and specificity of ELISA in syphilis test were higher than those of RPR(P<0.05).Conclusion Both ELISA and RPR have certain value in syphilis test,and the diagnostic efficiency of ELISA is relatively higher.

关 键 词：酶联免疫吸附测定法 快速血浆反应素试验 梅毒螺旋体 梅毒螺旋体抗体 非梅毒螺旋体抗体 

分 类 号：R446[医药卫生—诊断学]