基于六西格玛理论认知功能训练在阿尔茨海默病中的应用  

Application of cognitive function training based on six Sigma theory in Alzheimer′s disease

作　　者：雷婷 徐婷 王琛 LEI Ting;XU Ting;WANG Chen(Department of Geriatrics,Jiujiang University Affiliated Hospital,Jiangxi Province,Jiujiang 332000,China;Department of Neurology,Jiujiang University Affiliated Hospital,Jiangxi Province,Jiujiang 332000,China)

机构地区：[1]九江学院附属医院老年医学科,江西九江332000 [2]九江学院附属医院神经内科,江西九江332000

出　　处：《中国当代医药》2025年第8期168-171,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202311540)。

摘　　要：目的探讨基于六西格玛理论的认知功能训练对阿尔茨海默病(AD)患者的影响。方法选取2022年6月至2023年6月九江学院附属医院收治的100例AD患者作为研究对象,按照随机数字表法分为对照组和观察组,每组各50例。对照组实施传统的认知功能训练干预,观察组实施传统认知功能训练干预结合基于六西格玛理论的认知功能训练。比较两组认知功能、日常生活能力、生活质量、负性情绪、疾病不确定感。结果观察组干预后的简易精神状态量表(MMSE)评分、阿尔茨海默病生活质量量表(QOL-AD)评分均高于对照组,焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、日常生活能力评定量表(ADL)评分、不明确性评分、复杂性评分、中文版疾病不确定感量表(MUIS-A)总分均低于对照组,差异有统计学意义(P<0.05)。结论在AD患者中应用基于六西格玛理论的认知功能训练效果显著,可促进患者认知功能改善,减轻疾病不确定感,缓解负面情绪,有利于提高患者生活质量与日常生活能力。Objective To explore the effect of cognitive function training based on six Sigma theory on patients with Alzheimer's disease(AD).Methods A total of 100 AD patients admitted to the Jiujiang University Affiliated Hospital from June 2022 to June 2023 were selected as the study objects and divided into control group and observation group according to random number table method,with 50 cases in each group.The control group received traditional cognitive function training intervention,the observation group received traditional cognitive function training intervention combined with cognitive function training based on six Sigma theory.The cognitive function,daily living ability,quality of life,negative emotions,and disease uncertainty between two groups were compared.Results After intervention,the scores of mini-mental state examination(MMSE)and quality of life-Alzheimer's disease(QOL-AD)in the observation group were higher than those in the control group.The scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS),activity of daily living(ADL),uncertainty score,complexity score and the total scores of the Mishel uncertainty in illness scale-adult(MUIS-A)were lower than those of the control group,with statistical significances(P<0.05).Conclusion The application of cognitive function training based on six Sigma theory in AD patients has significant effects,which can promote the improvement of patients'cognitive function,reduce the uncertainty of disease,relieve negative emotions,and help improve patients'quality of life and daily living ability.

关 键 词：阿尔茨海默病 六西格玛管理理论 认知功能训练 生活质量 疾病不确定感 负性情绪 

分 类 号：R473[医药卫生—护理学]