基于互联网招募的孤独症谱系障碍专病队列建设概况及启示  

Overview and implications of the cohort construction for autism spectrum disorders based on Internet recruitment

作　　者：陈鑫 高慧 吴德[1] 陶芳标[2] CHEN Xin;GAO Hui;WU De;TAO Fangbiao(Department of Pediatrics,First Affiliated Hospital of Anhui Medical University,Hefei(230022),Anhui Province,China)

机构地区：[1]安徽医科大学第一附属医院儿科,合肥230022 [2]安徽医科大学公共卫生学院出生人口健康教育部重点实验室/环境与人口健康重点实验室

出　　处：《中国学校卫生》2025年第2期157-161,共5页Chinese Journal of School Health

基　　金：国家自然科学基金面上项目(82473641);安徽省高校优秀青年项目(2023AH030118)。

摘　　要：中国孤独症谱系障碍(ASD)专病队列的建设尚在起步阶段,依托儿童保健等诊疗过程采集的数据使其成本-效益不足。2000年后,基于互联网招募建设的美国西蒙斯推动ASD研究、美国早期ASD风险纵向调查和英国婴幼儿ASD同胞研究等,为中国建设ASD大样本专病队列提供了新思路。未来的研究可进一步探索和优化互联网招募的方法,建立更全面、准确的ASD专病队列。The construction of autism spectrum disorders(ASD)specialty cohorts in China is still in its infancy,and the cost-effectiveness is insufficient when relying on diagnostic and treatment processes of child health care to collect ample and high-quality data.After 2000,the United States Simons Foundation's ASD Research Initiative,the Early ASD Risk Longitudinal Investigation(EARLI),and the British ASD Study of Infant Siblings(BASIS),which have been built based on Internet recruitment,have provided new insight for the construction of large-sample ASD specialty cohorts in China.Future research can further explore and optimize the methods of Internet recruitment,and establish a more comprehensive and accurate ASD specialty cohorts.

关 键 词：孤独性障碍 队列研究 数据库 文献型 儿童 

分 类 号：R179[医药卫生—妇幼卫生保健] R748[医药卫生—公共卫生与预防医学] R395.3[哲学宗教—心理学]