鸭跖草化学成分研究  

Chemical constituents from Commelina communis

作　　者：易宏婷 梁丁美 雷彬 曾宏玲 陈钟文[1] 刘华[1] 刘峰[1] YI Hong-ting;LIANG Ding-mei;LEI Bin;ZENG Hong-ling;CHEN Zhong-wen;LIU Hua;LIU Feng(Jiangxi University of Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西中医药大学,江西南昌330004

出　　处：《中成药》2025年第3期827-833,共7页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金项目(81760706);江西省自然科学基金项目(2020BABL206146);江西省教育厅科技项目(GJJ211208)。

摘　　要：目的研究鸭跖草Commelina communis L.化学成分。方法鸭跖草95%乙醇提取物采用活性炭、硅胶、Sephadex LH-20、HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到17个化合物,分别鉴定为p-hydroxyl ethyl cinnamate(1)、p-hydroxybenzaldehyde(2)、vanillin(3)、4-hydroxy-2,3-dimethyl-2-nonen-4-olide(4)、hemeratrol A(5)、chakyunglupulin B(6)、chakyunglupulin A(7)、2-(2-hydroxyethyl)-3-methylfumaric acid(8)、N-cis-feruloyl tyramine(9)、N-trans-coumaroyltyramine(10)、5,6,7,3′,4′,5′-hexamethoxyflavone(11)、N-trans-sinapoyltyramine(12)、dihydro-feruloyltyramine(13)、N-trans-feruloyltyramine(14)、2-phenylethanol-β-D-glucoside(15)、quercetin-3-O-β-D-glucoside(16)、isorhamnetin-3-O-β-D-glucopyranoside(17)。结论化合物4~8、10、11为首次从鸭跖草属中分离得到,1、9、12~15为首次从该植物中分离得到。AIM To study the chemical constituents from Commelina communis L.METHODS The 95%ethanol extract from C.Communis was isolated and purified by activated charcoal,silica gel,Sephadex LH-20,and HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Seventeen compounds were isolated and identified as p-hydroxyl ethyl cinnamate(1),p-hydroxybenzaldehyde(2),vanillin(3),4-hydroxy-2,3-dimethyl-2-nonen-4-olide(4),hemeratrol A(5),chakyunglupulin B(6),chakyunglupulin A(7),2-(2-hydroxyethyl)-3-methylfumaric acid(8),N-cis-feruloyl tyramine(9),N-trans-coumaroyltyramine(10),5,6,7,3′,4′,5′-hexamethoxyflavone(11),N-trans-sinapoyltyramine(12),dihydro-feruloyltyramine(13),N-trans-feruloyltyramine(14),2-phenylethanol-β-D-glucoside(15),quercetin-3-O-β-D-glucoside(16),and isorhamnetin-3-O-β-D-glucopyranoside(17).CONCLUSION Compounds 4-8,10 and 11 are isolated from Commelina genus for the first time,and 1,9,12-15 are first isolated from this plant.

关 键 词：鸭跖草 化学成分 分离鉴定 

分 类 号：R284.1[医药卫生—中药学]