A portable,low-cost lactate measurement system  

一种便携、低成本乳酸测量系统

作　　者：WANG Qingqing PAN Yu YU Chuanxin WANG Yanyan ZHANG Kaikai LIU Sheng 王晴晴;潘玉;余传信;王妍延;张凯凯;刘升(淮北师范大学计算机科学与技术学院,安徽淮北235000;认知行为智能计算与应用工程研究中心,安徽淮北235000)

机构地区：[1]School of Computer Science and Technology,Huaibei Normal University,Huaibei 235000,China [2]Anhui Provincial Engineering Research Center of Cognitive Behavioral Intelligent Computing and Application,Huaibei 235000,China

出　　处：《Journal of Measurement Science and Instrumentation》2025年第1期37-46,共10页测试科学与仪器(英文版)

基　　金：supported by National Natural Science Foundation of China(No.62006092);Natural Science Research Project of Anhui Educational Committee(No.2023AH030081);2023 New Era Education Provincial Quality Engineering Project(Graduate Education)(No.2023cxcysj103);2024 New Era Education Provincial Quality Engineering Project(Graduate Education)。

摘　　要：Lactate,as a metabolite,plays a significant role in a number of fields,including medical diagnostics,exercise physiology and food science.Traditional methods for lactate measurement often involve expensive and cumbersome instrumentation.This study developed a portable and low-cost lactate measurement system,including independently detectable hardware circuits and user-friendly embedded software,computer,and smartphone applications.The experiment verified that the relative error of the detection current in the device circuit was less than 1%.The electrochemical performance was measured by comparing the[Fe(CN)_(6)]^(3−)/[Fe(CN)_(6)]^(4−)solution with the desktop electrochemical workstation CHI660E,and a nearly consistent chronoamperometry(CA)curve was obtained.Two modified lactate sensors were used for CA testing of lactate.Within the concentration range of 0.1 mmol·L^(−1)to 20 mmol·L^(−1),there was a good linear relationship between lactate concentration and steady-state current,with a correlation coefficient(R2)greater than 0.99 and good repeatability,demonstrating the reliability of the developed device.The lactate measurement system developed in this study not only provides excellent detection performance and reliability,but also achieves portability and low cost,providing a new solution for lactate measurement.乳酸作为代谢产物,在医学诊断、运动生理学和食品科学等领域扮演重要角色。传统的乳酸检测技术通常配备昂贵且笨重的仪器。为此,开发了一种便携式、低成本的乳酸测量系统,包括可独立检测的硬件电路和用户友好的嵌入式软件、电脑及手机应用程序。实验验证了该装置电路的检测电流相对误差小于1%,电化学性能通过对[Fe(CN)_(6)]^(3−)/[Fe(CN)_(6)]^(4−)溶液的测量,与台式电化学工作站CHI660E进行比较,得到了近乎一致的计时安培电流法(Chronoamperometry,CA)曲线。使用修饰的两种乳酸传感器:乳酸酶传感器(Enzymatic lactate sensor,ELS)和非酶乳酸传感器(Nonenzymatic lactate sensor,NLS)对乳酸进行CA测试,在0.1-20 mmol·L^(-1)的浓度范围内,乳酸浓度与稳态电流均呈现良好的线性关系,相关系数(R2)大于0.99,且重复性良好,体现了所研制装置的可靠性。本研究开发的乳酸测量系统在提供优异的检测性能和可靠性的同时,实现了便携性和低成本,为乳酸测量提供了一种新的解决方法。

关 键 词：lactate measurement portable device embedded development lactate sensor electrochemical analysis 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]