产前三维超声联合微血流成像诊断胎儿颅脑畸形  

Three-dimensional ultrasound combined with microvascular flow imaging for prenatal diagnosis of fetal intracranial anomalies

作　　者：崔元杰 郭翠霞[1] 李贞[1] 张娟[1] 张铁娟[1] 王克扬[2] 吴青青[1] 吴玉婷 孙丽娟[1] CUI Yuanjie;GUO Cuixia;LI Zhen;ZHANG Juan;ZHANG Tiejuan;WANG Keyang;WU Qingqing;WU Yuting;SUN Lijuan(Department of Ultrasound,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Hospital,Beijing 100026,China;Department of Radiology,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Hospital,Beijing 100026,China)

机构地区：[1]首都医科大学附属北京妇产医院、北京妇幼保健院超声科,北京100026 [2]首都医科大学附属北京妇产医院、北京妇幼保健院放射科,北京100026

出　　处：《中国医学影像技术》2025年第3期368-371,共4页Chinese Journal of Medical Imaging Technology

基　　金：高层次公共卫生技术人才建设项目(学科骨干-02-06)。

摘　　要：目的观察产前三维超声联合微血流成像诊断胎儿颅脑畸形的价值。方法回顾性分析118胎经颅脑MRI/引产后标本解剖确诊并接受产前超声检查的颅脑畸形胎儿,观察其二维、三维超声和微血流成像表现,分析三维超声联合微血流成像诊断胎儿颅脑畸形的准确率。结果产前三维超声联合微血流成像诊断胎儿颅脑畸形的准确率为93.22%(110/118),诊断孤立性及非孤立性颅脑畸形的准确率分别为97.47%(77/79)及84.62%(33/39);漏诊6胎脑皮质发育畸形(结节性硬化症1胎、脑沟回形态异常4胎和脑裂畸形1胎)及1胎颅内软化灶,将1胎颅后窝蛛网膜囊肿误诊为大枕大池。结论产前三维超声联合微血流成像诊断胎儿颅脑畸形具有较高准确率。Objective To observe the value of three-dimensional ultrasound combined with microvascular flow imaging for prenatal diagnosis of fetal intracranial anomalies.Methods Totally 118 fetuses with intracranial anomalies diagnosed through cranial MRI/induced labor specimen dissection who underwent prenatal ultrasound examination were retrospectively enrolled.Two-dimensional,three-dimensional ultrasound and microvascular flow imaging manifestations of fetal intracranial anomalies were observed,and the accuracy of three-dimensional ultrasound combined with microvascular flow imaging for prenatal diagnosis of fetal intracranial anomalies was analyzed.Results The accuracy of three-dimensional ultrasound combined with microvascular flow imaging for prenatal diagnosis of fetal intracranial anomalies was 93.22%(110/118),of isolated and non-isolated intracranial anomalies was 97.47%(77/79)and 84.62%(33/39),respectively.Six fetuses were missed diagnosis of malformations of cortical development(1 fetus of tuberous sclerosis,4 of abnormal morphology of the sulci gyrus and 1 of schizencephaly)and 1 fetus of intracranial softening lesion,while posterior fossa arachnoid cyst in 1 fetus was misdiagnosed as mega cisterna magna.Conclusion The accuracy of three-dimensional ultrasound combined with microvascular flow imaging for prenatal diagnosis of fetal intracranial anomalies was relatively high.

关 键 词：胎儿 神经系统畸形 超声检查 

分 类 号：R714.53[医药卫生—妇产科学] R445.1[医药卫生—临床医学]