嗜血分枝杆菌皮肤感染一例  

Skin infection caused by Mycobacterium haemophilum:a case report

作　　者：茹颖莹 周开华 邹晴 李卫峰 RU Yingying;ZHOU Kaihua;ZOU Qing;LI Weifeng(General Medical 363 Hospital,Chengdu 610000,China)

机构地区：[1]通用医疗三六三医院皮肤科,四川成都610000

出　　处：《中国麻风皮肤病杂志》2025年第4期254-256,共3页China Journal of Leprosy and Skin Diseases

摘　　要：患者,男,65岁。无明显诱因右手背部丘疹、结节伴破溃6个月余。自行外用红霉素软膏及口服头孢克肟治疗,效果欠佳。皮肤科查体见右手背部水肿性红斑及丘疱疹,部分破溃形成溃疡。组织病理提示炎性肉芽组织增生,组织抗酸染色阳性,高通量基因检查提示嗜血分枝杆菌感染。给予左氧氟沙星、克拉霉素和利福平联合治疗,并行局部清创术。治疗2个月后皮损基本消退,6个月后皮损愈合且未复发。A 65-year-old male presented with papules,nodules and ulceration on the back of the right hand for more than 6 months without any obvious cause.The patient had been treated with erythromycin ointment and oral cefixime,but the effect was not good.Dermatological examination showed edematous erythema and herpetic herps on the back of the right hand,partially ruptured and formed ulcers.Histopathology indicated inflammatory granulation tissue hyperplasia,tissue acid-fast staining was positive,and high-throughput gene examination indicated hemophilus infection.Levofloxacin,clarithromycin and rifampicin were treated together with local debridement.The skin lesions basically subsided after 2 months of the treatment,and the skin lesions healed without recurrence after 6 months'treatment.

关 键 词：非结核分枝杆菌 嗜血分枝杆菌 

分 类 号：R632[医药卫生—外科学]