Environmental Temperature and the Risk of Hand,Foot,and Mouth Disease Transmission in the Yangtze River Region of China  

作　　者：Yanqing Yang Min Chen Jin Li Kaiqi Liu Xueyan Guo Xin Xu Qian Liang Xinglu Wu Suwen Lei Jing Li 

机构地区：[1]School of Public Health,Shandong Second Medical University,Weifang 261053,Shandong,China [2]Weifang People’s Hospital,Shandong Second Medical University,Weifang 261000,Shandong,China [3]Office of Health Standards,Chinese Center for Disease Control and Prevention,Beijing 102206,China [4]Weifang Center for Disease Control and Prevention,Weifang 261053,Shandong,China [5]School of Stomatology,Shandong Second Medical University,Weifang 261053,Shandong,China

出　　处：《Biomedical and Environmental Sciences》2025年第3期290-302,共13页生物医学与环境科学(英文版)

基　　金：The funding of this study was of the 2021 Shandong Province Higher Education“Young Innovative Talent Introduction and Training Program”(Public Health Safety Risk Assessment and Response Innovation Team);the annual education and teaching reform and research project at the school level of Shandong Second Medical University(No.2023YBD006);the Public Health Standards Research and Development Project of the National Disease Control and Prevention Bureau(No.233007);the Public Health Standards Revision and Supervision Support Project of the National Disease Control and Prevention Bureau (No.242401).

摘　　要：Objective To assess health equity in the Yangtze River region to improve understanding of the correlation between hand,foot,and mouth disease(HFMD)and socioeconomic factors.Methods From 2014–2016,data on HFMD incidence,population statistics,economic indicators,and meteorology from 26 cities along the Yangtze River were analyzed.A multi-city random-effects meta-analysis was performed to study the relationship between temperature and HFMD transmission,and health equity was assessed with respect to socio-economic impact.Results Over the study period,919,458 HFMD cases were reported,with Shanghai(162,303)having the highest incidence and Tongling(5,513)having the lowest.Males were more commonly affected(male-to-female ratio,1.49:1).The exposure-response relationship had an M-shaped curve,with two HFMD peaks occurring at 4°C and 26°C.The relative risk had two peaks at 1.30°C(1.834,95%CI:1.204–2.794)and 31.4°C(1.143,95%CI:0.901–1.451),forming an M shape,with the first peak higher than the second.The most significant impact of temperature on HFMD was observed between–2°C and 18.1°C.The concentration index(0.2463)indicated moderate concentration differences,whereas the Theil index(0.0418)showed low inequality in distribution.Conclusion The incidence of HFMD varied across cities,particularly with changes in temperature.Economically prosperous areas showed higher risks,indicating disparities.Targeted interventions in these areas are crucial for mitigating the risk of HFMD.

关 键 词：Hand foot and mouth disease Temperature META-ANALYSIS Concentration index Theil index 

分 类 号：R72[医药卫生—儿科]