Impact of Endometrial Polyps on Pregnancy Outcomes in Patients with Endometriosis and Infertility: A Systematic Review and Meta-analysis  

作　　者：Liang Zhang Qian Han Meiru Bao Ying Wu 

机构地区：[1]Beijing Hospital of Integrated Traditional Chinese and Western Medicine,Beijing 100039,China [2]Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing 100026,China [3]Meishan Hospital of Traditional Chinese Medicine,Meishan 620000,Sichuan,China

出　　处：《Biomedical and Environmental Sciences》2025年第3期341-350,共10页生物医学与环境科学(英文版)

摘　　要：Objective To evaluate the impact of endometrial polyps(EP)on postoperative pregnancy outcomes in infertile women with endometriosis(EMs).Methods PubMed,Embase,The Cochrane Library,CNKI,VIP,SinoMed,and WanFang Data databases were searched to include clinical studies on the effect of EP on pregnancy outcomes in patients with EMs,published before August 31,2020.A meta-analysis was performed using Rev Man 5.3 software after two investigators independently screened the literature,extracted information,and evaluated the risk of bias of the included studies.Results The meta-analysis included ten studies(651 and 1,040 in the combined EP and uncomplicated EP groups,respectively).The spontaneous pregnancy rate,clinical pregnancy rate,and live birth rate were significantly lower in the group with combined EPs than in the group without combined EPs[Odd’s ratio(OR)=0.63,95%confidence interval(CI):0.50–0.80,P=0.0001;OR=0.63,95%CI:0.48–0.84,P=0.001;OR=0.63,95%CI:0.42–0.96,P=0.03],and the rate of embryonic abortion was significantly higher than that in the uncomplicated EP group[OR=3.10,95%CI:1.52–6.32,P=0.002].Conclusion EP may adversely affect pregnancy outcomes in patients with infertility and EMs.Even after surgical treatment,EP can still reduce natural pregnancy,clinical pregnancy,and live birth rates in infertile women with EMs and increase the risk of embryo arrest in these women.

关 键 词：ENDOMETRIOSIS Endometrial polyps INFERTILITY Pregnancy outcome META-ANALYSIS 

分 类 号：R71[医药卫生—妇产科学]