2021年至2023年许昌市人民医院呼吸内科患者抗感染药物所致药品不良反应分析  

Analysis of Adverse Drug Reactions Caused by Anti-Infective Drugs in Respiratory Department of Xuchang People's Hospital From 2021 to 2023

作　　者：王文文 谢勇涛 WANG Wen-wen;XIE Yong-tao(Department of Pharmacy,Xuchang People's Hospital,Xuchang 461000,China)

机构地区：[1]许昌市人民医院药学部,许昌461000

出　　处：《四川解剖学杂志》2024年第6期14-16,共3页Sichuan Journal of Anatomy

摘　　要：目的:分析2021年至2023年许昌市人民医院呼吸内科患者抗感染药物所致药品不良反应情况.方法:选取2021年1月至2023年10月于本院呼吸内科就诊后发生药品不良反应的72例患者作为研究对象.统计并分析患者的给药途径、抗感染药物种类、药品不良反应发生时间、药品不良反应累及器官/系统.结果:72例发生药品不良反应患者中,以静脉滴注和静脉注射给药为主,分别占44.44%、31.94%;使用头孢类、喹诺酮类、青霉素类药物患者占比较高,分别为31.94%、29.17%、11.11%;药品不良反应发生时间在1d内占比最高,为80.56%;药品不良反应累及皮肤及附件、血管及血液系统、胃肠系统的占比较高,分别为52.78%、12.50%、11.11%.结论:2021年至2023年许昌市人民医院呼吸内科患者抗感染药物所致药品不良反应主要累及皮肤及附件、血管及血液系统和胃肠系统,且发生时间大多在1d以内;头孢类、喹诺酮类、青霉素类抗感染药物应用和静脉给药途径的药品不良反应发生风险较高.Objective:To analyze the adverse drug reactions caused by anti-infective drugs in the respiratory department of Xuchang People's Hospital from 2021 to 2023.Methods:A total of 72 patients with adverse drug reactions after visiting the respiratory department of our hospital from January 2021 to October 2023 were selected as research objects.The route of administration,the type of anti-infective drugs,the time of adverse drug reactions,and the organs/systems involved in adverse drug reactions were counted and analyzed.Results:Among the 72 patients with adverse drug reactions,intravenous infusion and intravenous injection were the main routes of administration,accounting for 44.44%and 31.94%,respectively.The proportion of patients using cephalosporins,quinolones,and penicillins was relatively high,with 31.94%,29.17%,and 11.11%,respectively.The occurrence time of adverse drug reactions accounted for the highest proportion within 1 day,which was 80.56%.The proportion of adverse drug reactions involving skin and appendages,vascular and blood system,and gastrointestinal system was relatively high,which were 52.78%,12.50%,and 11.11%,respectively.Conclusion:The adverse drug reactions caused by anti-infective drugs in the respiratory department of Xuchang People's Hospital from 2021 to 2023 mainly involved skin and appendages,vascular and blood system,and gastrointestinal system,and most of them occurred within 1 day.The use of cephalosporins,quinolones,penicillins anti-infective drugs and intravenous administration routes have a high risk of adverse drug reactions.

关 键 词：抗感染药物 药品不良反应 呼吸内科 

分 类 号：R47[医药卫生—护理学]