成都市男男性行为人群抑郁与涉药性行为的相关性分析  

Relationship between depression and sexual drug use in men who have sex with men in Chengdu

作　　者：刘瑞雯 朱洋 张博 陈晓婷 郝春[1] 顾菁[1] 李菁华 曹望楠[3] 侯丰苏 Liu Ruiwen;Zhu Yang;Zhang Bo;Chen Xiaoting;Hao Chun;Gu Jing;Li Jinghua;Cao Wangnan;Hou Fengsu(Department of Medical Statistics,School of Public Health,Global Health Institute,Center for Health Information Research,Sun Yat-sen University,Guangzhou 510080,China;Guangzhou Joint Research Center for Disease Surveillance,Early Warning and Risk Assessment,Guangzhou 510080,China;Department of Social Medicine and Health Education,School of Public Health,Peking University,Beijing 100191,China;Corning Hospital of Shenzhen,Public Health Department of Shenzhen Mental Health Center,Shenzhen 518020,China)

机构地区：[1]中山大学公共卫生学院医学统计学系/中山大学全球卫生研究中心/中山大学卫生信息研究中心,广州510080 [2]广州市疾病监测预警与风险评估联合研究中心,广州510080 [3]北京大学公共卫生学院社会医学与健康教育系,北京100191 [4]深圳市康宁医院/深圳市精神卫生中心公共卫生部,深圳518020

出　　处：《中华流行病学杂志》2025年第3期462-468,共7页Chinese Journal of Epidemiology

基　　金：广东省自然科学基金(2023A1515030093);中山大学中央高校基本科研业务费专项(24ykqb007)。

摘　　要：目的调查成都市男男性行为人群(MSM)中抑郁与涉药性行为的流行情况,并探索两者之间的相关性。方法2021年11月至2022年5月,在MSM中招募1277名研究对象,收集其社会人口学特征、抑郁情况及涉药性行为等信息。采用单因素和多因素logistic回归模型分析MSM抑郁与涉药性行为的相关性。结果在1277名研究对象中,被评估为轻度、中度和重度抑郁者分别占39.4%(503名)、15.3%(196名)和13.4%(171名);研究对象自报过去6个月有涉药性行为的比例为34.8%(444/1277)。多因素logistic回归模型分析结果显示,与无抑郁症状者相比,被评估为轻度抑郁者(aOR=1.67,95%CI:1.24~2.23)、中度抑郁者(OR=1.50,95%CI:1.02~2.19)和重度抑郁者(aOR=1.56,95%CI:1.04~2.32)发生涉药性行为的可能性较高,抑郁与涉药性行为呈正相关。结论成都MSM的抑郁和发生涉药性行为的比例均较高,抑郁与涉药性行为呈正相关。应重点关注MSM中的抑郁和涉药性行为,开展针对性的干预。Objective To investigate the prevalence of sexual drug use in men who have sex with men(MSM)in Chengdu and analyze the relationship between depression and sexual drug use.Methods A total of 1277 MSM were recruited between November 2021 and May 2022.Questionnaire was used to collect information about their demographic characteristics,depression status and sexual drug use behavior.Univariate and multivariate logistic regression models were used to analyze the relationship between depression and sexual drug use.Results In the 1277 MSM,assessment identified 503 mild depression cases(39.4%),196 moderate depression cases(15.3%)and 171 severe depression cases(13.4%)and 444 MSM(34.8%)reported sexual drug use in the past 6 months.Multivariate logistic regression models showed that compared with non-depression,mild depression(aOR=1.67,95%CI:1.24-2.23),moderate depression(aOR=1.50,95%CI:1.02-2.19)and severe depression(aOR=1.56,95%CI:1.04-2.32)were positively associated with sexual drug use.Conclusions The prevalence of depression and sexual drug use were high in MSM in Chengdu.There was a positive correlation between depression and sexual drug use.It is necessary to pay close attention to depression and sexual drug use and conduct targeted intervention in MSM.

关 键 词：男男性行为人群 涉药性行为 抑郁 

分 类 号：R51[医药卫生—内科学]