Does the outcome of acupuncture differ according to the location of sham needling points in acupuncture trials for migraine?A systematic review and network meta-analysis  

作　　者：Boram Lee Chan-Young Kwon Hye Won Lee Arya Nielsen LSusan Wieland Tae-Hun Kim Stephen Birch Terje Alraek Myeong Soo Lee 

机构地区：[1]KM Science Research Division,Korea Institute of Oriental Medicine,Daejeon,34054,Republic of Korea [2]Department of Oriental Neuropsychiatry,Dong-Eui University College of Korean Medicine,Busan,47227,Republic of Korea [3]KM Convergence Research Division,Korea Institute of Oriental Medicine,Daejeon,34054,Republic of Korea [4]Department of Family Medicine&Community Health,Icahn School of Medicine at Mount Sinai,New York,10029,USA [5]Center for Integrative Medicine,University of Maryland School of Medicine,Baltimore,Maryland,21201,USA [6]Korean Medicine Clinical Trial Center,Korean Medicine Hospital,Kyung Hee University,Seoul,02447,Republic of Korea [7]School of Health Sciences,Kristiania University College,Oslo,0107,Norway [8]Department of Community Medicine,Faculty of Health Sciences,National Research Center in Complementary and Alternative Medicine(NAFKAM),Institute of Health Sciences,Tromsø,9037,Norway

出　　处：《Frontiers of Medicine》2025年第1期53-63,共11页医学前沿(英文版)

基　　金：supported by the Korea Institute of Oriental Medicine(Nos.KSN2121211 and KSN23314112);LSW was supported by the National Center for Complementary and Integrative Health of the National Institutes of Health(No.R24 AT001293);The funders had no role in the design and conduct of the study,the collection,management,analysis,and interpretation of the data,the preparation,review,and approval of the manuscript,or the decision to submit the manuscript for publication.

摘　　要：Various acupuncture clinical trials have been conducted on migraine;however,the conclusions remain controversial especially when acupuncture was compared with sham acupuncture.Sham acupuncture is sometimes performed at the same acupuncture points used for verum acupuncture despite the evidence on acupuncture point specificity.Four databases were searched for sham acupuncture or waiting list-controlled acupuncture trials for migraine on December 25,2023.Sham acupuncture was classified according to the needling points:sham acupuncture therapy at verum points(SATV)or at sham points(SATS).Network meta-analysis was performed based on the frequentist framework for headache pain intensity and response rate.A total of 18 studies involving 1936 participants were analyzed.Headache pain intensity and response rate were significantly improved in verum acupuncture compared with SATS.However,there was no significant difference between SATV and verum acupuncture.When comparing SATS and SATV,there was no significant difference in headache pain intensity and response rate;however,the results were in favor of SATV.The effect of the risk of bias on the certainty of evidence between verum and sham acupunctures was judged to be generally low.SATV should not be misused as a placebo control to evaluate the efficacy of acupuncture.

关 键 词：acupuncture therapy MIGRAINE migraine disorders sham acupuncture PLACEBO 

分 类 号：R24[医药卫生—中医临床基础]