中药汤剂煎法的科学内涵研究进展  

Research progress on scientific connotations of decocting methods in traditional Chinese medicine decoction

作　　者：王凤霞 陈芳雯 沈成英 岳鹏飞 申宝德 WANG Feng-xia;CHEN Fang-wen;SHEN Cheng-ying;YUE Peng-fei;SHEN Bao-de(Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Chinese Medicine,Nanchang 330004,China;State Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine,Nanchang 330103,China;Department of Pharmacy,Jiangxi Provincial People′s Hospital(the First Affiliated Hospital of Nanchang Medical College),Nanchang 330006,China;Research and Development Department,Jiangzhong Pharmaceutical Co.,Ltd.,Nanchang 330103,China)

机构地区：[1]江西中医药大学现代中药制剂教育部重点实验室,江西南昌330004 [2]经典名方现代中药创制全国重点实验室,江西南昌330103 [3]江西省人民医院(南昌医学院第一附属医院)药学部,江西南昌330006 [4]江中药业股份有限公司研发部,江西南昌330103

出　　处：《中国中药杂志》2025年第4期994-999,共6页China Journal of Chinese Materia Medica

基　　金：江西省自然科学基金项目(20232BAB216139);国家自然科学基金项目(82460852,82260848);江西中医药大学校级科技创新团队发展计划项目(CXTD22006);江西中医药大学校级研究生创新专项(JZYC23S64)。

摘　　要：中药汤剂的疗效与煎法密切相关,正确认识中药汤剂的煎法及其科学内涵,对指导汤剂的煎煮应用及基于传统汤剂的现代中药制剂开发具有重要意义。中药汤剂的煎煮不仅是中药化学成分的热水提取过程,还伴随着复杂的化学和物理变化,并形成汤液的复杂多相态体系,显著影响中药的吸收和疗效。该文从中药汤剂煎煮引起的化学成分变化、相态差异,以及吸收行为与药理毒理改变等角度综述中药汤剂煎法的科学内涵研究进展,以期为中药汤剂的煎法研究及科学内涵阐释提供借鉴和参考,推动中药传统汤剂研究的创新与发展,促进现代中药制剂的设计与开发。The therapeutic effects of traditional Chinese medicine(TCM)decoction is closely related to its decocting methods.A correct understanding of the scientific connotations of decocting methods in TCM is of great significance for guiding the application of decoctions and the development of modern TCM preparations based on decoctions.The decocting process is not only a hot water extraction process of chemical components but also accompanied by complex chemical and physical changes,forming a complex multiphase system and significantly affecting the absorption and therapeutic effect of TCM.This article reviews the research progress in scientific connotations of decocting methods in TCM from the perspectives of chemical composition changes,phase state differences,absorption behavior changes,and pharmacological and toxicological changes caused by decocting.This review is expected to provide implications for studying decocting methods and their scientific interpretation,boost the innovation and development of TCM decoctions,and promote the design and development of modern TCM preparations.

关 键 词：汤剂 化学成分 相态差异 吸收 药理毒理 研究进展 

分 类 号：R28[医药卫生—中药学]