基于Logistic回归影响感染性休克患者预后的危险因素分析  

Analysis of Risk Factors Affecting the Prognosis of Patients with Septic Shock Based on Logistic Regression

作　　者：杨茂新 YANG Maoxin(Department of Intensive Care Medicine,Guangzhou University of Traditional Chinese Medicine Maoming Hospital(Maoming Hospital of Traditional Chinese Medicine),Maoming 525000,Guangdong,China)

机构地区：[1]广州中医药大学茂名医院(茂名市中医院)重症医学科,广东茂名525000

出　　处：《系统医学》2024年第24期107-110,共4页Systems Medicine

摘　　要：目的 探讨影响感染性休克患者预后的危险因素。方法 回顾性选取2023年1月—2024年1月广州中医药大学茂名医院收治的180例感染性休克患者的临床资料,根据患者出院时预后将其分为存活组(135例)和死亡组(45例)。进行单因素和多因素Logistic回归分析感染性休克患者预后的危险因素。结果 单因素分析:两组的年龄、高血压史、糖尿病史、血乳酸水平、血小板水平、急性生理与慢性健康状况评估(Acute Physiology and Chronic Health Evaluation II, APACHE II)评分、序贯器官衰竭评估(Sequential Organ Failure Assessment,SOFA)评分、6h内最低pH值比较,差异有统计学意义(P均<0.05)。多因素分析:年龄≥60岁(OR=2.438)、合并高血压(OR=2.038)、合并糖尿病(OR=1.958)、高血乳酸水平(OR=3.180)、APACHE II评分(OR=2.059)、SOFA评分(OR=3.473)、6 h内最低pH值(OR=2.300)为影响感染性休克患者预后的危险因素(P均<0.05)。结论 年龄≥60岁、合并高血压、合并糖尿病、高血乳酸水平、APACHE II评分、SOFA评分、6 h内最低pH值为影响感染性休克患者预后的危险因素。Objective To explore the risk factors affecting the prognosis of patients with septic shock.Methods The clinical data of 180 patients with septic shock admitted to Guangzhou University of Traditional Chinese Medicine Maoming Hospital from January 2023 to January 2024 were retrospectively selected.According to the prognosis at dis‐charge,the patients were divided into survival group(135 cases)and death group(45 cases).The risk factors of prog‐nosis in patients with septic shock were analyzed by univariate and multivariate logistic regression.Results Univariate analysis:There were significant differences in age,history of hypertension,history of diabetes,blood lactate level,platelet level,Acute Physiology and Chronic Health Evaluation II(APACHE II)score,Sequential Organ Failure As‐sessment(SOFA)score,and lowest pH value within 6 hours between the two groups(all P<0.05).Multivariate analysis showed that age≥60 years old(OR=2.438),hypertension(OR=2.038),diabetes(OR=1.958),high blood lactic acid level(OR=3.180),APACHE II score(OR=2.059),SOFA score(OR=3.473),and the lowest pH value within 6 hours(OR=2.300)were risk factors affecting the prognosis of patients with septic shock(all P<0.05).Conclusion Age≥60 years old,hypertension,diabetes,high blood lactic acid level,APACHE II score,SOFA score and the lowest pH value within 6 hours were risk factors affecting the prognosis of patients with septic shock.

关 键 词：感染性休克 预后 危险因素 血乳酸水平 预测价值 

分 类 号：R459.7[医药卫生—急诊医学]