不同血糖控制水平对2型糖尿病合并脓毒症患者预后的影响  

Effect of Different Blood Glucose Control Levels on the Prognosis of Patients with Type 2 Diabetes Mellitus Complicated with Sepsis

作　　者：庄佩元 姚金印 黄金花[1] ZHUANG Peiyuan;YAO Jinyin;HUANG Jinhua(Department of Intensive Care Medicine,Jinjiang Hospital,Jinjiang 362261,Fujian,China)

机构地区：[1]晋江市医院重症医学科,福建晋江362261

出　　处：《糖尿病新世界》2025年第4期82-84,88,共4页Diabetes New World

摘　　要：目的 探究不同血糖控制水平对2型糖尿病合并脓毒症患者预后的影响。方法 选取2023年2月—2024年2月晋江市医院重症医学科收治的90例2型糖尿病合并脓毒症患者为研究对象,根据治疗方式的不同分成两组,各45例。对照组为常规血糖控制,观察组为强化血糖控制。对比两组预后不良情况、急性生理及慢性健康状况评分、B型尿钠肽、C-反应蛋白、空腹血糖、餐后2 h血糖水平。结果 两组预后不良情况总发生率比较,差异无统计学意义(P>0.05)。治疗后,观察组B型尿钠肽、C-反应蛋白、空腹血糖、餐后2 h血糖水平及急性生理及慢性健康状况评分均低于对照组,差异均有统计学意义(P均<0.05)。结论 不同血糖控制对2型糖尿病合并脓毒症患者的预后有显著影响,强化血糖控制能有效稳定血糖水平,减少不良预后的发生,临床应用价值较高。Objective To explore the effect of different blood glucose control levels on the prognosis of patients with type 2 diabetes mellitus complicated with sepsis.Methods A total of 90 patients with type 2 diabetes mellitus complicated with sepsis admitted to the Department of Intensive Care Medicine of Jinjiang Hospital from February 2023 to February 2024 were selected as the research objects.According to the different treatment methods,they were divided into two groups,with 45 cases in each group.The control group was routine blood glucose control,and the observation group was intensive blood glucose control.The poor prognosis,Acute Physiology and Chronic Health Evaluation Ⅱ,B-type natriuretic peptide,C-reactive protein,fasting plasma glucose,and 2-hour postprandial plasma glucose levels were compared between the two groups.Results There was no significant difference in the total incidence of poor prognosis between the two groups(P>0.05).After treatment,the levels of B-type natriuretic peptide,C-reactive protein,fasting plasma glucose,2-hour postprandial plasma glucose and Acute Physiology and Chronic Health Evaluation Ⅱscore in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Different blood glucose control has a significant effect on the prognosis of patients with type 2 diabetes mellitus complicated with sepsis.Intensive blood glucose control can effectively stabilize blood glucose levels and reduce the occurrence of poor prognosis,and has high clinical application value.

关 键 词：不同血糖控制水平 2型糖尿病 脓毒症 预后影响 

分 类 号：R587[医药卫生—内分泌]