阿卡波糖片结合甘精胰岛素治疗老年糖尿病的药效价值分析  

Analysis of the Efficacy Value of Acarbose Tablets Combined with Insulin Glargine in the Treatment of Elderly Diabetes Mellitus

作　　者：林敏 李鑫 郑海琴 LIN Min;LI Xin;ZHENG Haiqin(Department of Pharmaceutical Sciences,Liuhe District People's Hospital,Nanjing 211500,Jiangsu,China)

机构地区：[1]南京市六合区人民医院药剂科,江苏南京211500

出　　处：《糖尿病新世界》2025年第4期92-95,共4页Diabetes New World

摘　　要：目的 评估阿卡波糖加甘精胰岛素方案在老年糖尿病治疗中的具体疗效。方法 选取2023年1—12月于南京市六合区人民医院就诊的100例老年糖尿病患者,按照不同治疗手段分为对照组(50例,甘精胰岛素治疗)、观察组(50例,阿卡波糖结合甘精胰岛素治疗),比较两组血糖水平、不良反应发生情况、临床疗效。结果 观察组糖化血红蛋白、餐后2 h血糖、空腹血糖水平均更低,治疗总有效率更高,差异均有统计学意义(P均<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 甘精胰岛素联合阿卡波糖治疗老年糖尿病控糖效果更佳,不良反应发生率更低,治疗效果显著。Objective To evaluate the specific efficacy of acarbose plus insulin glargine regimen in the treatment of elderly diabetes mellitus.Methods A total of 100 elderly patients with diabetes mellitus who were treated in Liuhe District People's Hospital from January to December 2023 were selected.According to different treatment methods,they were divided into control group(50 cases,insulin glargine treatment) and observation group(50 cases,acarbose combined with insulin glargine treatment).The blood glucose levels,adverse reactions and clinical efficacy of the two groups were compared.Results The levels of glycated hemoglobin A1c,2-hour postprandial blood glucose and fasting blood glucose in the observation group were lower,the total effective rate of treatment was higher,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Insulin glargine combined with acarbose in the treatment of elderly diabetes mellitus has better glucose control effect,lower incidence of adverse reactions,and significant treatment effect.

关 键 词：糖尿病 甘精胰岛素 阿卡波糖 血糖水平 不良反应 

分 类 号：R473.71[医药卫生—护理学]