利拉鲁肽治疗2型糖尿病合并肥胖患者的效果及体重改善情况研究  

Efficacy and Weight Improvement of Liraglutide in the Treatment of Type 2 Diabetes Mellitus with Obesity

作　　者：顾萍 陆闻婷 黄雯雅 GU Ping;LU Wenting;HUANG Wenya(Department of Pharmacy,the First People's Hospital of Taicang City,Taicang 215400,Jiangsu,China;Department of Endocrinology,the First People's Hospital of Taicang City,Taicang 215400,Jiangsu,China)

机构地区：[1]太仓市第一人民医院药剂科,江苏太仓215400 [2]太仓市第一人民医院内分泌科,江苏太仓215400

出　　处：《糖尿病新世界》2025年第4期99-101,共3页Diabetes New World

摘　　要：目的 分析运用利拉鲁肽治疗2型糖尿病合并肥胖患者的临床效果。方法 按照治疗方法的不同,将2023年1月—2024年6月太仓市第一人民医院收治的2型糖尿病合并肥胖患者60例分为观察组(30例,常规对症治疗+利拉鲁肽治疗)、对照组(30例,常规对症治疗)。比较两组血糖指标、体重状况、不良反应发生率。结果 治疗后,相比于对照组,观察组空腹血糖、餐后2 h血糖、腹围、体重指数水平均更低,差异均有统计学意义(P均<0.05)。观察组的不良反应发生率与对照组相比,差异无统计学意义(P>0.05)。结论 在2型糖尿病合并肥胖患者的临床治疗中,利拉鲁肽联合用药可帮助患者控制血糖水平,减轻体重,临床效果较好。Objective To analyze the clinical effect of liraglutide in the treatment of patients with type 2 diabetes mellitus complicated with obesity.Methods According to the different treatment methods,a total of 60 patients with type 2 diabetes mellitus complicated with obesity admitted to the First People's Hospital of Taicang City from January 2023 to June 2024 were divided into observation group(30 cases,routine symptomatic treatment+liraglutide treatment)and control group(30 cases,routine symptomatic treatment).The blood glucose indexes,weight status and incidence of adverse reactions were compared between the two groups.Results After treatment,compared with the control group,the levels of fasting plasma glucose,2-hour postprandial plasma glucose,abdominal circumference and body mass index of the observation group were lower,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P>0.05).Conclusion In the clinical treatment of patients with type 2 diabetes mellitus complicated with obesity,the combination of liraglutide can help patients control blood glucose levels and lose weight,and the clinical effect is better.

关 键 词：利拉鲁肽 2型糖尿病 肥胖 体重 

分 类 号：R587[医药卫生—内分泌]