生物合成人胰岛素对妊娠期糖尿病血糖水平的影响研究  

Study on the Effect of Biosynthetic Human Insulin on Blood Glucose Level in Gestational Diabetes Mellitus

作　　者：张凤娇 陈燕华 连小英 ZHANG Fengjiao;CHEN Yanhua;LIAN Xiaoying(Department of Obstetrics,Quanzhou First Hospital,Quanzhou 362000,Fujian,China)

机构地区：[1]泉州市第一医院产科,福建泉州362000

出　　处：《糖尿病新世界》2025年第2期82-84,共3页Diabetes New World

摘　　要：目的探究将生物合成人胰岛素应用至妊娠期糖尿病治疗中,对患者血糖水平的改善效果。方法回顾性选取2023年1月—2024年6月泉州市第一医院收治的110例妊娠期糖尿病患者的临床资料,按照治疗方案的不同分为对照组(n=55,实施地特胰岛素治疗)和观察组(n=55,实施生物合成人胰岛素治疗)。对比两组不良妊娠结局、不良反应发生率、血糖水平。结果治疗后,观察组餐后2 h血糖、空腹血糖水平均更低,差异均有统计学意义(P均<0.05)。观察组不良妊娠结局发生率及不良反应发生率均更低,差异均有统计学意义(P均<0.05)。结论生物合成人胰岛素用于妊娠期糖尿病患者治疗,可减少不良妊娠结局及不良反应发生率,降低血糖水平。Objective To explore the effect of biosynthetic human insulin on the improvement of blood glucose level in patients with gestational diabetes mellitus.Methods The clinical data of 110 patients with gestational diabetes mel-litus admitted to Quanzhou First Hospital from January 2023 to June 2024 were retrospectively selected and divided into control group(n=55,treated with insulin detemir)and observation group(n=55,treated with biosynthetic human insulin)according to different treatment regimens.The adverse pregnancy outcomes,incidence of adverse reactions and blood glucose level were compared between the two groups.Results After treatment,the levels of 2-hour post-prandial blood glucose and fasting blood glucose in the observation group were lower,and the differences were statisti-cally significant(both P<0.05).The incidence of adverse pregnancy outcomes and adverse reactions in the observation group were lower,and the differences were statistically significant(both P<0.05).Conclusion Biosynthetic human in-sulin for the treatment of patients with gestational diabetes mellitus can reduce the incidence of adverse pregnancy out-comes and adverse reactions,and reduce blood glucose level.

关 键 词：生物合成人胰岛素 妊娠期糖尿病 血糖水平 不良妊娠结局 

分 类 号：R587.1[医药卫生—内分泌]