微量泵持续泵入胰岛素与二甲双胍对行左氧氟沙星治疗的2型糖尿病合并慢性阻塞性肺疾病老年患者疗效对比分析  

Comparative Analysis of the Efficacy of Continuous Infusion of Insulin by Micropump and Metformin in Elderly Patients with Type 2 Diabetes Melli⁃tus Complicated with Chronic Obstructive Pulmonary Disease Treated with Levofloxacin

作　　者：林翠玲 傅燕华 蔡娜萍 LIN Cuiling;FU Yanhua;CAI Naping(Department of Respiratory and Critical Care Medicine,Anxi County Hospital,Quanzhou 362400,Fujian,China)

机构地区：[1]安溪县医院呼吸与危重症医学科,福建泉州362400

出　　处：《糖尿病新世界》2025年第2期88-91,共4页Diabetes New World

摘　　要：目的分析行左氧氟沙星治疗的2型糖尿病合并慢性阻塞性肺疾病(简称慢阻肺)老年患者接受微量泵持续泵入胰岛素与二甲双胍的治疗效果。方法回顾性选取2023年5月—2024年6月安溪县医院收治的120例2型糖尿病合并慢阻肺老年患者的临床资料,按治疗方案的不同分为两组,均60例。对照组采用二甲双胍与左氧氟沙星治疗,观察组在对照组基础上联合微量泵持续泵入胰岛素治疗。对比两组血糖水平、血糖控制效果、急性生理与慢性健康评分和生活质量。结果治疗2周后,两组空腹血糖、餐后2 h血糖、糖化血红蛋白水平比较,差异均无统计学意义(P均>0.05)。治疗2周后,观察组血糖控制效果高于对照组,急性生理与慢性健康和生活质量评分均低于对照组,差异均有统计学意义(P均<0.05)。结论在常规抗感染治疗基础上,二甲双胍与微量泵持续泵入胰岛素治疗都可以改善患者血糖水平,但微量泵持续泵入胰岛素可起到更为显著的血糖控制效果,进一步降低疾病严重程度,改善生活质量。Objective To analyze the effect of continuous pumping of insulin by micropump and metformin in elderly patients with type 2 diabetes mellitus complicated with chronic obstructive pulmonary disease treated with levofloxa-cin.Methods The clinical data of 120 elderly patients with type 2 diabetes mellitus complicated with chronic obstruc-tive pulmonary disease admitted to Anxi County Hospital from May 2023 to June 2024 were retrospectively selected and divided into two groups according to different treatment schemes,with 60 cases in each group.The control group was treated with metformin and levofloxacin,and the observation group was treated with continuous pumping of insu-lin by micropump on the basis of the control group.The blood glucose level,blood glucose control effect,acute physi-ology and chronic health score and quality of life were compared between the two groups.Results After 2 weeks of treatment,There were no significant differences in fasting plasma glucose,2-hour postprandial plasma glucose and glycated hemoglobin A1c levels between the two groups(all P>0.05).After 2 weeks of treatment,the blood glucose control effect of the observation group was higher than that of the control group,and the scores of acute physiology and chronic health and quality of life were lower than those of the control group,the differences were statistically signifi-cant(all P<0.05).Conclusion On the basis of conventional anti-infection treatment,metformin and continuous infu-sion of insulin by micropump can improve the blood glucose level of patients,but continuous infusion of insulin by mi-cropump can achieve more significant blood glucose control effect,further reduce the severity of the disease and im-prove the quality of life.

关 键 词：左氧氟沙星 2型糖尿病 慢性阻塞性肺疾病 

分 类 号：R587.2[医药卫生—内分泌]