老年性耳聋与认知障碍的相关性分析  

Correlation analysis between presbycusis and cognitive impairment

作　　者：管萌欢 冯娟[1] 李林格[1] 孟圆圆 张鼎昊 张华[1] GUAN Menghuan;FENG Juan;LI Linge;MENG Yuanyuan;ZHANG Dinghao;ZHANG Hua(Department of Otolaryngology,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院耳鼻喉科,乌鲁木齐830054

出　　处：《新疆医科大学学报》2025年第3期338-343,共6页Journal of Xinjiang Medical University

基　　金：国家重点研发计划重点专项(2023YFC3604200,2023YFC3604203)。

摘　　要：目的探讨老年性耳聋(Presbycusis,PC)患者听力水平不同程度下降对认知能力的影响,分析PC与认知障碍的关系。方法选取2023年1月-2024年5月新疆医科大学第一附属医院耳鼻喉科就诊的300名60岁以上老年人,收集患者的听力学检查结果。Logistic回归模型分析认知状态的影响因素,Spearman相关性分析听力水平与认知状态的关系。结果年龄、文化程度、经济状况、职业性质、高血压、日常娱乐时间、听力损失程度均为认知状态的影响因素(P<0.05);多因素Logistic回归分析结果显示,高血压病史、文化程度是认知功能降低的独立危险因素(P<0.05),高血压病史、文化程度、日常娱乐时间和听力损失是痴呆的独立危险因素(P<0.05);Spearman相关性分析结果显示,听力损失与简易精神状态量表(MMSE)评分呈负相关(r=-0.247,P<0.01);单因素分析结果显示,PTA受损程度与定向力、记忆力、注意力和计算力、回忆能力、语言能力(包括命名能力、复述能力、三步命令、阅读能力、结构能力)差异有统计学意义(P<0.01)。结论PC患者听力水平不同程度下降是痴呆的危险因素,PC与认知障碍呈负相关,老年人听力下降应及早干预从而防治痴呆的发生。Objective To explore the effect of decreased hearing level in presbycusis patients on cognitive ability,and to analyze the relationship between presbycusis and cognitive impairment.Methods 300 elderly people over 60 years old treated in the hospital from January 2023 to May 2024 were selected to collect the audiological examination results.Logistic regression model analyzed the factors affecting cognitive status,and Spearman correlation analyzed the relationship between hearing level and cognitive status.Results Age,educational level,economic status,occupational nature,hypertension,daily entertainment time and hearing loss were all influencing factors of cognitive status(P<0.05).The results of the multivariate Logistic regression analysis showed that,history of hypertension and educational level were independent risk factors for reduced cognitive function(P<0.05);history of hypertension,educational level,daily recreational time and hearing loss were the independent risk factors for dementia(P<0.05).The results of the Spearman-correlation analysis showed that,hearing loss was negatively associated with MMSE(r=-0.247,P<0.01).The results of the univariate analysis showed that,the difference between the impaired PTA and orientation power,memory,attention and computing power,recall ability,language ability(including naming ability,retelling ability,3-step command,reading ability and structural ability)was statistically significant(P<0.01).Conclusion Different decrease of hearing level in PC patients is a risk factor for dementia,and PC is negatively associated with cognitive impairment.Hearing loss in the elderly should prevent the occurrence of dementia as soon as possible.

关 键 词：老年性耳聋 年龄相关性耳聋 认知障碍 简易精神智能状态量表 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]