经皮耳迷走神经刺激在围术期镇痛中的应用研究进展  

Advances in the application of transcutaneous auricular vagus nerve stimulation in perioperative analgesia

作　　者：陈姝凝 朱鼎芳 王力峰 叶军明 CHEN Shu-ning;ZHU Ding-fang;WANG Li-feng;YE Jun-ming(The First Clinical Medical College of Gannan Medical University;Anaesthesia and Surgery Centre,The First Affiliated Hospital of Gannan Medical University;Ganzhou Key Laboratory of Anaesthesiology,Ganzhou,Jiangxi 341000)

机构地区：[1]赣南医科大学第一临床医学院 [2]赣南医科大学第一附属医院麻醉手术中心 [3]赣州市麻醉学重点实验室,江西赣州341000

出　　处：《赣南医科大学学报》2025年第2期189-194,共6页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：经皮耳迷走神经刺激(Transcutaneous auricular vagus nerve stimulation,taVNS)是一种向外耳迷走神经耳支支配的皮肤感受野施加电流来治疗疾病的一种干预措施。近年来随着舒适化医疗发展,taVNS在临床中的应用优势日益展现。研究报道taVNS可通过激活迷走神经改善围术期疼痛,减轻患者术后负担,作为一种无创自主神经调控的干预措施,taVNS不仅操作简便无创,无毒副作用,且经济实用。目前关于临床应用taVNS进行围术期镇痛的具体效果尚存在争议。本文结合近年来国内外研究进展,从迷走神经耳支的解剖生理、taVNS在疼痛调节中的作用机制、在围术期镇痛中的临床研究进展3方面进行综述,旨在为taVNS在围术期镇痛的临床应用和研究提供参考。Transcutural auricular vagus nerve stimulation(taVNS)is an intervention measure to treat diseases by applying current to the skin receptive field dominated by the auricular branches of the external ear vagus nerve.In recent years,with the development of comfort diagnostic and therapeutic procedure,taVNS has shown increasing application advantages in clinical practice.It is reported that taVNS can improve perioperative pain by activating vagus nerve and reduce the postoperative burden of patients.As a non-invasive intervention measure of autonomic nervous regulation,taVNS is not only simple,non-invasive and non-toxic,but also economical and practical.At present,the specific effect of clinical application of taVNS for perioperative analgesia is still controversial.Based on the research progress at home and abroad in recent years,this paper systematically reviews the anatomical physiology of auricular branch of vagus nerve,the mechanism of taVNS in pain regulation and the clinical research progress in perioperative analgesia,aimingn to provide reference for the clinical application and research of taVNS in perioperative analgesia.

关 键 词：经皮耳迷走神经刺激 围术期 镇痛 

分 类 号：R614[医药卫生—麻醉学]